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Role of mGlu2 in the 5-HT2A receptor-dependent antipsychotic activity of clozapine in mice.
Hideshima KS, Hojati A, Saunders JM, On DM, de la Fuente Revenga M, Shin JM, Sánchez-González A, Dunn CM, Pais AB, Pais AC, Miles MF, Wolstenholme JT, González-Maeso J. Hideshima KS, et al. Psychopharmacology (Berl). 2018 Nov;235(11):3149-3165. doi: 10.1007/s00213-018-5015-4. Epub 2018 Sep 12. Psychopharmacology (Berl). 2018. PMID: 30209534 Free PMC article.
Identification of a serotonin/glutamate receptor complex implicated in psychosis.
González-Maeso J, Ang RL, Yuen T, Chan P, Weisstaub NV, López-Giménez JF, Zhou M, Okawa Y, Callado LF, Milligan G, Gingrich JA, Filizola M, Meana JJ, Sealfon SC. González-Maeso J, et al. Nature. 2008 Mar 6;452(7183):93-7. doi: 10.1038/nature06612. Epub 2008 Feb 24. Nature. 2008. PMID: 18297054 Free PMC article.
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia.
Moreno JL, Miranda-Azpiazu P, García-Bea A, Younkin J, Cui M, Kozlenkov A, Ben-Ezra A, Voloudakis G, Fakira AK, Baki L, Ge Y, Georgakopoulos A, Morón JA, Milligan G, López-Giménez JF, Robakis NK, Logothetis DE, Meana JJ, González-Maeso J. Moreno JL, et al. Sci Signal. 2016 Jan 12;9(410):ra5. doi: 10.1126/scisignal.aab0467. Sci Signal. 2016. PMID: 26758213 Free PMC article.
Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists.
Younkin J, Gaitonde SA, Ellaithy A, Vekariya R, Baki L, Moreno JL, Shah S, Drossopoulos P, Hideshima KS, Eltit JM, González-Maeso J, Logothetis DE, Dukat M, Glennon RA. Younkin J, et al. ACS Chem Neurosci. 2016 Sep 21;7(9):1292-9. doi: 10.1021/acschemneuro.6b00162. Epub 2016 Jul 19. ACS Chem Neurosci. 2016. PMID: 27385190 Free PMC article.
Differential effects of antipsychotic and propsychotic drugs on prepulse inhibition and locomotor activity in Roman high- (RHA) and low-avoidance (RLA) rats.
Oliveras I, Sánchez-González A, Sampedro-Viana D, Piludu MA, Río-Alamos C, Giorgi O, Corda MG, Aznar S, González-Maeso J, Gerbolés C, Blázquez G, Cañete T, Tobeña A, Fernández-Teruel A. Oliveras I, et al. Psychopharmacology (Berl). 2017 Mar;234(6):957-975. doi: 10.1007/s00213-017-4534-8. Epub 2017 Feb 2. Psychopharmacology (Berl). 2017. PMID: 28154892 Free PMC article.
113 results