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Metabolic alterations in Parkinson's disease astrocytes.
Sonninen TM, Hämäläinen RH, Koskuvi M, Oksanen M, Shakirzyanova A, Wojciechowski S, Puttonen K, Naumenko N, Goldsteins G, Laham-Karam N, Lehtonen M, Tavi P, Koistinaho J, Lehtonen Š. Sonninen TM, et al. Among authors: goldsteins g. Sci Rep. 2020 Sep 2;10(1):14474. doi: 10.1038/s41598-020-71329-8. Sci Rep. 2020. PMID: 32879386 Free PMC article.
Dysfunction of Cellular Proteostasis in Parkinson's Disease.
Lehtonen Š, Sonninen TM, Wojciechowski S, Goldsteins G, Koistinaho J. Lehtonen Š, et al. Among authors: goldsteins g. Front Neurosci. 2019 May 10;13:457. doi: 10.3389/fnins.2019.00457. eCollection 2019. Front Neurosci. 2019. PMID: 31133790 Free PMC article. Review.
Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy.
Huuskonen MT, Loppi S, Dhungana H, Keksa-Goldsteine V, Lemarchant S, Korhonen P, Wojciechowski S, Pollari E, Valonen P, Koponen J, Takashima A, Landreth G, Goldsteins G, Malm T, Koistinaho J, Kanninen KM. Huuskonen MT, et al. Among authors: goldsteins g. Sci Rep. 2016 Sep 14;6:33176. doi: 10.1038/srep33176. Sci Rep. 2016. PMID: 27624652 Free PMC article.
Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis.
Korhonen P, Pollari E, Kanninen KM, Savchenko E, Lehtonen Š, Wojciechowski S, Pomeshchik Y, Van Den Bosch L, Goldsteins G, Koistinaho J, Malm T. Korhonen P, et al. Among authors: goldsteins g. IBRO Rep. 2019 Jan 11;6:74-86. doi: 10.1016/j.ibror.2019.01.005. eCollection 2019 Jun. IBRO Rep. 2019. PMID: 30705990 Free PMC article.
An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo.
Keuters MH, Keksa-Goldsteine V, Dhungana H, Huuskonen MT, Pomeshchik Y, Savchenko E, Korhonen PK, Singh Y, Wojciechowski S, Lehtonen Š, Kanninen KM, Malm T, Sirviö J, Muona A, Koistinaho M, Goldsteins G, Koistinaho J. Keuters MH, et al. Among authors: goldsteins g. Sci Rep. 2021 Feb 10;11(1):3518. doi: 10.1038/s41598-021-81741-3. Sci Rep. 2021. PMID: 33568697 Free PMC article.
Neuron-astrocyte transmitophagy is altered in Alzheimer's disease.
Lampinen R, Belaya I, Saveleva L, Liddell JR, Rait D, Huuskonen MT, Giniatullina R, Sorvari A, Soppela L, Mikhailov N, Boccuni I, Giniatullin R, Cruz-Haces M, Konovalova J, Koskuvi M, Domanskyi A, Hämäläinen RH, Goldsteins G, Koistinaho J, Malm T, Chew S, Rilla K, White AR, Marsh-Armstrong N, Kanninen KM. Lampinen R, et al. Among authors: goldsteins g. Neurobiol Dis. 2022 Aug;170:105753. doi: 10.1016/j.nbd.2022.105753. Epub 2022 May 13. Neurobiol Dis. 2022. PMID: 35569719 Free article.
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