Goldfarb NE - Search Results

1

Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration.

Quiliano M, Mendoza A, Fong KY, Pabón A, Goldfarb NE, Fabing I, Vettorazzi A, López de Cerain A, Dunn BM, Garavito G, Wright DW, Deharo E, Pérez-Silanes S, Aldana I, Galiano S. Quiliano M, et al. Among authors: goldfarb ne. Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):184-198. doi: 10.1016/j.ijpddr.2016.09.004. Epub 2016 Sep 28. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27718413 Free PMC article.

2

Expression, purification, and characterization of aspartic endopeptidases: Plasmodium plasmepsins and "short" recombinant human pseudocathepsin.

Beyer BB, Goldfarb NE, Dunn BM. Beyer BB, et al. Among authors: goldfarb ne. Curr Protoc Protein Sci. 2004 Aug;Chapter 21:21.14.1-21.14.24. doi: 10.1002/0471140864.ps2114s32. Curr Protoc Protein Sci. 2004. PMID: 18429256

3

Hydroxyethylamine Based Phthalimides as New Class of Plasmepsin Hits: Design, Synthesis and Antimalarial Evaluation.

Singh AK, Rathore S, Tang Y, Goldfarb NE, Dunn BM, Rajendran V, Ghosh PC, Singh N, Latha N, Singh BK, Rawat M, Rathi B. Singh AK, et al. Among authors: goldfarb ne. PLoS One. 2015 Oct 26;10(10):e0139347. doi: 10.1371/journal.pone.0139347. eCollection 2015. PLoS One. 2015. PMID: 26502278 Free PMC article.

4

Electrostatic switches that mediate the pH-dependent conformational change of "short" recombinant human pseudocathepsin D.

Goldfarb NE, Lam MT, Bose AK, Patel AM, Duckworth AJ, Dunn BM. Goldfarb NE, et al. Biochemistry. 2005 Dec 6;44(48):15725-33. doi: 10.1021/bi0511686. Biochemistry. 2005. PMID: 16313175 Free PMC article.

5

Defective hydrophobic sliding mechanism and active site expansion in HIV-1 protease drug resistant variant Gly48Thr/Leu89Met: mechanisms for the loss of saquinavir binding potency.

Goldfarb NE, Ohanessian M, Biswas S, McGee TD Jr, Mahon BP, Ostrov DA, Garcia J, Tang Y, McKenna R, Roitberg A, Dunn BM. Goldfarb NE, et al. Biochemistry. 2015 Jan 20;54(2):422-33. doi: 10.1021/bi501088e. Epub 2015 Jan 7. Biochemistry. 2015. PMID: 25513833 Free PMC article.

6

Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution.

Liu Z, Huang X, Hu L, Pham L, Poole KM, Tang Y, Mahon BP, Tang W, Li K, Goldfarb NE, Dunn BM, McKenna R, Fanucci GE. Liu Z, et al. Among authors: goldfarb ne. J Biol Chem. 2016 Oct 21;291(43):22741-22756. doi: 10.1074/jbc.M116.747568. Epub 2016 Aug 30. J Biol Chem. 2016. PMID: 27576689 Free PMC article.

7

A template-based approach to inhibitors of calpain 2, 20S proteasome, and HIV-1 protease.

Jones SA, Neilsen PM, Siew L, Callen DF, Goldfarb NE, Dunn BM, Abell AD. Jones SA, et al. Among authors: goldfarb ne. ChemMedChem. 2013 Dec;8(12):1918-21. doi: 10.1002/cmdc.201300387. Epub 2013 Oct 15. ChemMedChem. 2013. PMID: 24130198

8

Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c).

Naffin-Olivos JL, Daab A, White A, Goldfarb NE, Milne AC, Liu D, Baikovitz J, Dunn BM, Rengarajan J, Petsko GA, Ringe D. Naffin-Olivos JL, et al. Among authors: goldfarb ne. Biochemistry. 2017 May 2;56(17):2304-2314. doi: 10.1021/acs.biochem.6b01066. Epub 2017 Apr 7. Biochemistry. 2017. PMID: 28346784 Free PMC article.

9

Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2.

Naffin-Olivos JL, Georgieva M, Goldfarb N, Madan-Lala R, Dong L, Bizzell E, Valinetz E, Brandt GS, Yu S, Shabashvili DE, Ringe D, Dunn BM, Petsko GA, Rengarajan J. Naffin-Olivos JL, et al. PLoS Pathog. 2014 May 15;10(5):e1004132. doi: 10.1371/journal.ppat.1004132. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24830429 Free PMC article.

10

Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease.

Li M, Gustchina A, Matúz K, Tözsér J, Namwong S, Goldfarb NE, Dunn BM, Wlodawer A. Li M, et al. Among authors: goldfarb ne. FEBS J. 2011 Nov;278(22):4413-24. doi: 10.1111/j.1742-4658.2011.08364.x. Epub 2011 Oct 10. FEBS J. 2011. PMID: 21951660 Free PMC article.

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