Gokhale R - Search Results

1

A brain atlas of synapse protein lifetime across the mouse lifespan.

Bulovaite E, Qiu Z, Kratschke M, Zgraj A, Fricker DG, Tuck EJ, Gokhale R, Koniaris B, Jami SA, Merino-Serrais P, Husi E, Mendive-Tapia L, Vendrell M, O'Dell TJ, DeFelipe J, Komiyama NH, Holtmaat A, Fransén E, Grant SGN. Bulovaite E, et al. Among authors: gokhale r. Neuron. 2022 Dec 21;110(24):4057-4073.e8. doi: 10.1016/j.neuron.2022.09.009. Epub 2022 Oct 5. Neuron. 2022. PMID: 36202095 Free PMC article.

2

A brainwide atlas of synapses across the mouse life span.

Cizeron M, Qiu Z, Koniaris B, Gokhale R, Komiyama NH, Fransén E, Grant SGN. Cizeron M, et al. Among authors: gokhale r. Science. 2020 Jul 17;369(6501):270-275. doi: 10.1126/science.aba3163. Epub 2020 Jun 11. Science. 2020. PMID: 32527927 Free PMC article.

3

Dissecting and exploiting intermodular communication in polyketide synthases.

Gokhale RS, Tsuji SY, Cane DE, Khosla C. Gokhale RS, et al. Science. 1999 Apr 16;284(5413):482-5. doi: 10.1126/science.284.5413.482. Science. 1999. PMID: 10205055

4

Purification and characterization of bimodular and trimodular derivatives of the erythromycin polyketide synthase.

Pieper R, Gokhale RS, Luo G, Cane DE, Khosla C. Pieper R, et al. Among authors: gokhale rs. Biochemistry. 1997 Feb 18;36(7):1846-51. doi: 10.1021/bi962324z. Biochemistry. 1997. PMID: 9048569

5

Functional orientation of the acyltransferase domain in a module of the erythromycin polyketide synthase.

Gokhale RS, Lau J, Cane DE, Khosla C. Gokhale RS, et al. Biochemistry. 1998 Feb 24;37(8):2524-8. doi: 10.1021/bi971887n. Biochemistry. 1998. PMID: 9485401

6

Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase.

Gokhale RS, Hunziker D, Cane DE, Khosla C. Gokhale RS, et al. Chem Biol. 1999 Feb;6(2):117-25. doi: 10.1016/S1074-5521(99)80008-8. Chem Biol. 1999. PMID: 10021418

7

Role of linkers in communication between protein modules.

Gokhale RS, Khosla C. Gokhale RS, et al. Curr Opin Chem Biol. 2000 Feb;4(1):22-7. doi: 10.1016/s1367-5931(99)00046-0. Curr Opin Chem Biol. 2000. PMID: 10679375 Review.

8

Tolerance and specificity of polyketide synthases.

Khosla C, Gokhale RS, Jacobsen JR, Cane DE. Khosla C, et al. Among authors: gokhale rs. Annu Rev Biochem. 1999;68:219-53. doi: 10.1146/annurev.biochem.68.1.219. Annu Rev Biochem. 1999. PMID: 10872449 Review.

9

Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel.

Tsai SC, Miercke LJ, Krucinski J, Gokhale R, Chen JC, Foster PG, Cane DE, Khosla C, Stroud RM. Tsai SC, et al. Among authors: gokhale r. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14808-13. doi: 10.1073/pnas.011399198. Proc Natl Acad Sci U S A. 2001. PMID: 11752428 Free PMC article.

10

Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase.

Yin Y, Gokhale R, Khosla C, Cane DE. Yin Y, et al. Among authors: gokhale r. Bioorg Med Chem Lett. 2001 Jun 18;11(12):1477-9. doi: 10.1016/s0960-894x(00)00529-1. Bioorg Med Chem Lett. 2001. PMID: 11412964

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