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Page 1
Distinct longevity mechanisms across and within species and their association with aging.
Tyshkovskiy A, Ma S, Shindyapina AV, Tikhonov S, Lee SG, Bozaykut P, Castro JP, Seluanov A, Schork NJ, Gorbunova V, Dmitriev SE, Miller RA, Gladyshev VN. Tyshkovskiy A, et al. Among authors: gladyshev vn. Cell. 2023 Jun 22;186(13):2929-2949.e20. doi: 10.1016/j.cell.2023.05.002. Epub 2023 Jun 3. Cell. 2023. PMID: 37269831
Biological age is increased by stress and restored upon recovery.
Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN. Poganik JR, et al. Among authors: gladyshev vn. Cell Metab. 2023 May 2;35(5):807-820.e5. doi: 10.1016/j.cmet.2023.03.015. Epub 2023 Apr 21. Cell Metab. 2023. PMID: 37086720 Free PMC article.
Chemically induced reprogramming to reverse cellular aging.
Yang JH, Petty CA, Dixon-McDougall T, Lopez MV, Tyshkovskiy A, Maybury-Lewis S, Tian X, Ibrahim N, Chen Z, Griffin PT, Arnold M, Li J, Martinez OA, Behn A, Rogers-Hammond R, Angeli S, Gladyshev VN, Sinclair DA. Yang JH, et al. Among authors: gladyshev vn. Aging (Albany NY). 2023 Jul 12;15(13):5966-5989. doi: 10.18632/aging.204896. Epub 2023 Jul 12. Aging (Albany NY). 2023. PMID: 37437248 Free PMC article.
Biomarkers of aging for the identification and evaluation of longevity interventions.
Moqri M, Herzog C, Poganik JR; Biomarkers of Aging Consortium; Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. Moqri M, et al. Among authors: gladyshev vn. Cell. 2023 Aug 31;186(18):3758-3775. doi: 10.1016/j.cell.2023.08.003. Cell. 2023. PMID: 37657418 Free PMC article. Review.
AgeMeta: Quantitative Gene Expression Database of Mammalian Aging.
Tikhonov S, Batin M, Gladyshev VN, Dmitriev SE, Tyshkovskiy A. Tikhonov S, et al. Among authors: gladyshev vn. Biochemistry (Mosc). 2024 Feb;89(2):313-321. doi: 10.1134/S000629792402010X. Biochemistry (Mosc). 2024. PMID: 38622098 Free article.
Epigenetic clocks, aging, and cancer.
Johnstone SE, Gladyshev VN, Aryee MJ, Bernstein BE. Johnstone SE, et al. Among authors: gladyshev vn. Science. 2022 Dec 23;378(6626):1276-1277. doi: 10.1126/science.abn4009. Epub 2022 Dec 22. Science. 2022. PMID: 36548410
Loss of epigenetic information as a cause of mammalian aging.
Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, Ross JM, Coppotelli G, Meer MV, Rogers-Hammond R, Vera DL, Lu YR, Pippin JW, Creswell ML, Dou Z, Xu C, Mitchell SJ, Das A, O'Connell BL, Thakur S, Kane AE, Su Q, Mohri Y, Nishimura EK, Schaevitz L, Garg N, Balta AM, Rego MA, Gregory-Ksander M, Jakobs TC, Zhong L, Wakimoto H, El Andari J, Grimm D, Mostoslavsky R, Wagers AJ, Tsubota K, Bonasera SJ, Palmeira CM, Seidman JG, Seidman CE, Wolf NS, Kreiling JA, Sedivy JM, Murphy GF, Green RE, Garcia BA, Berger SL, Oberdoerffer P, Shankland SJ, Gladyshev VN, Ksander BR, Pfenning AR, Rajman LA, Sinclair DA. Yang JH, et al. Among authors: gladyshev vn. Cell. 2023 Jan 19;186(2):305-326.e27. doi: 10.1016/j.cell.2022.12.027. Epub 2023 Jan 12. Cell. 2023. PMID: 36638792 Free PMC article.
Mitigating age-related somatic mutation burden.
Vijg J, Schumacher B, Abakir A, Antonov M, Bradley C, Cagan A, Church G, Gladyshev VN, Gorbunova V, Maslov AY, Reik W, Sharifi S, Suh Y, Walsh K. Vijg J, et al. Among authors: gladyshev vn. Trends Mol Med. 2023 Jul;29(7):530-540. doi: 10.1016/j.molmed.2023.04.002. Epub 2023 Apr 29. Trends Mol Med. 2023. PMID: 37121869 Free article. Review.
A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan.
Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, Markovski A, Sun S, Yao H, Sankaran VG, Gladyshev VN, Brooke RT, Horvath S, Griffith EC, Hrvatin S. Jayne L, et al. Among authors: gladyshev vn. bioRxiv [Preprint]. 2024 Mar 25:2024.03.20.585828. doi: 10.1101/2024.03.20.585828. bioRxiv. 2024. PMID: 38585858 Free PMC article. Preprint.
450 results