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Peripheral inflammation preceeding ischemia impairs neuronal survival through mechanisms involving miR-127 in aged animals.
Loppi S, Korhonen P, Bouvy-Liivrand M, Caligola S, Turunen TA, Turunen MP, Hernandez de Sande A, Kołosowska N, Scoyni F, Rosell A, García-Berrocoso T, Lemarchant S, Dhungana H, Montaner J, Koistinaho J, Kanninen KM, Kaikkonen MU, Giugno R, Heinäniemi M, Malm T. Loppi S, et al. Among authors: giugno r. Aging Cell. 2021 Jan;20(1):e13287. doi: 10.1111/acel.13287. Epub 2020 Dec 28. Aging Cell. 2021. PMID: 33369048 Free PMC article.
Human genetic diversity alters off-target outcomes of therapeutic gene editing.
Cancellieri S, Zeng J, Lin LY, Tognon M, Nguyen MA, Lin J, Bombieri N, Maitland SA, Ciuculescu MF, Katta V, Tsai SQ, Armant M, Wolfe SA, Giugno R, Bauer DE, Pinello L. Cancellieri S, et al. Among authors: giugno r. Nat Genet. 2023 Jan;55(1):34-43. doi: 10.1038/s41588-022-01257-y. Epub 2022 Dec 15. Nat Genet. 2023. PMID: 36522432 Free PMC article.
Extracellular Vesicles Mediate Mesenchymal Stromal Cell-Dependent Regulation of B Cell PI3K-AKT Signaling Pathway and Actin Cytoskeleton.
Adamo A, Brandi J, Caligola S, Delfino P, Bazzoni R, Carusone R, Cecconi D, Giugno R, Manfredi M, Robotti E, Marengo E, Bassi G, Takam Kamga P, Dal Collo G, Gatti A, Mercuri A, Arigoni M, Olivero M, Calogero RA, Krampera M. Adamo A, et al. Among authors: giugno r. Front Immunol. 2019 Mar 12;10:446. doi: 10.3389/fimmu.2019.00446. eCollection 2019. Front Immunol. 2019. PMID: 30915084 Free PMC article.
Construction and Analysis of miRNA Regulatory Networks.
Mensi A, Bonnici V, Caligola S, Giugno R. Mensi A, et al. Among authors: giugno r. Methods Mol Biol. 2019;1970:121-167. doi: 10.1007/978-1-4939-9207-2_9. Methods Mol Biol. 2019. PMID: 30963492
PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia.
Konttinen H, Cabral-da-Silva MEC, Ohtonen S, Wojciechowski S, Shakirzyanova A, Caligola S, Giugno R, Ishchenko Y, Hernández D, Fazaludeen MF, Eamen S, Budia MG, Fagerlund I, Scoyni F, Korhonen P, Huber N, Haapasalo A, Hewitt AW, Vickers J, Smith GC, Oksanen M, Graff C, Kanninen KM, Lehtonen S, Propson N, Schwartz MP, Pébay A, Koistinaho J, Ooi L, Malm T. Konttinen H, et al. Among authors: giugno r. Stem Cell Reports. 2019 Oct 8;13(4):669-683. doi: 10.1016/j.stemcr.2019.08.004. Epub 2019 Sep 12. Stem Cell Reports. 2019. PMID: 31522977 Free PMC article.
Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation.
Kolosowska N, Gotkiewicz M, Dhungana H, Giudice L, Giugno R, Box D, Huuskonen MT, Korhonen P, Scoyni F, Kanninen KM, Ylä-Herttuala S, Turunen TA, Turunen MP, Koistinaho J, Malm T. Kolosowska N, et al. Among authors: giugno r. J Neuroinflammation. 2020 Jun 19;17(1):194. doi: 10.1186/s12974-020-01870-w. J Neuroinflammation. 2020. PMID: 32560730 Free PMC article.
TUBE Project: Transport-Derived Ultrafines and the Brain Effects.
Martikainen MV, Aakko-Saksa P, van den Broek L, Cassee FR, Carare RO, Chew S, Dinnyes A, Giugno R, Kanninen KM, Malm T, Muala A, Nedergaard M, Oudin A, Oyola P, Pfeiffer TV, Rönkkö T, Saarikoski S, Sandström T, Schins RPF, Topinka J, Yang M, Zeng X, Westerink RHS, Jalava PI. Martikainen MV, et al. Among authors: giugno r. Int J Environ Res Public Health. 2021 Dec 28;19(1):311. doi: 10.3390/ijerph19010311. Int J Environ Res Public Health. 2021. PMID: 35010571 Free PMC article.
Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer's Disease Patients.
Lampinen R, Fazaludeen MF, Avesani S, Örd T, Penttilä E, Lehtola JM, Saari T, Hannonen S, Saveleva L, Kaartinen E, Fernández Acosta F, Cruz-Haces M, Löppönen H, Mackay-Sim A, Kaikkonen MU, Koivisto AM, Malm T, White AR, Giugno R, Chew S, Kanninen KM. Lampinen R, et al. Among authors: giugno r. Cells. 2022 Feb 15;11(4):676. doi: 10.3390/cells11040676. Cells. 2022. PMID: 35203328 Free PMC article.
Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer's Disease Patients.
Lampinen R, Górová V, Avesani S, Liddell JR, Penttilä E, Závodná T, Krejčík Z, Lehtola JM, Saari T, Kalapudas J, Hannonen S, Löppönen H, Topinka J, Koivisto AM, White AR, Giugno R, Kanninen KM. Lampinen R, et al. Among authors: giugno r. Int J Mol Sci. 2022 Apr 8;23(8):4123. doi: 10.3390/ijms23084123. Int J Mol Sci. 2022. PMID: 35456941 Free PMC article.
100 results