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Metabolic activation and colitis pathogenesis is prevented by lymphotoxin β receptor expression in neutrophils.
Riffelmacher T, Giles DA, Zahner S, Dicker M, Andreyev AY, McArdle S, Perez-Jeldres T, van der Gracht E, Murray MP, Hartmann N, Tumanov AV, Kronenberg M. Riffelmacher T, et al. Among authors: giles da. Mucosal Immunol. 2021 May;14(3):679-690. doi: 10.1038/s41385-021-00378-7. Epub 2021 Feb 10. Mucosal Immunol. 2021. PMID: 33568785 Free PMC article.
Targeting Cytokine Signaling and Lymphocyte Traffic via Small Molecules in Inflammatory Bowel Disease: JAK Inhibitors and S1PR Agonists.
Pérez-Jeldres T, Tyler CJ, Boyer JD, Karuppuchamy T, Yarur A, Giles DA, Yeasmin S, Lundborg L, Sandborn WJ, Patel DR, Rivera-Nieves J. Pérez-Jeldres T, et al. Among authors: giles da. Front Pharmacol. 2019 Mar 13;10:212. doi: 10.3389/fphar.2019.00212. eCollection 2019. Front Pharmacol. 2019. PMID: 30930775 Free PMC article. Review.
CD4+-mediated colitis in mice is independent of the GPR183 and GPR18 pathways.
Dicker M, Li Y, Giles DA, Verstichel G, Castelan VC, Ascui-Gac G, Chou TF, Perez-Jeldres T, Cheroutre H, Kronenberg M. Dicker M, et al. Among authors: giles da. Front Immunol. 2022 Oct 28;13:1034648. doi: 10.3389/fimmu.2022.1034648. eCollection 2022. Front Immunol. 2022. PMID: 36389671 Free PMC article.
PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease.
Moreno-Fernandez ME, Giles DA, Oates JR, Chan CC, Damen MSMA, Doll JR, Stankiewicz TE, Chen X, Chetal K, Karns R, Weirauch MT, Romick-Rosendale L, Xanthakos SA, Sheridan R, Szabo S, Shah AS, Helmrath MA, Inge TH, Deshmukh H, Salomonis N, Divanovic S. Moreno-Fernandez ME, et al. Among authors: giles da. Cell Metab. 2021 Jun 1;33(6):1187-1204.e9. doi: 10.1016/j.cmet.2021.04.018. Epub 2021 May 17. Cell Metab. 2021. PMID: 34004162 Free PMC article.
Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice.
Harley IT, Giles DA, Pfluger PT, Burgess SL, Walters S, Hembree J, Raver C, Rewerts CL, Downey J, Flick LM, Stankiewicz TE, McAlees JW, Wills-Karp M, Balfour Sartor R, Divanovic S, Tschöp MH, Karp CL. Harley IT, et al. Among authors: giles da. Mol Metab. 2013 May 10;2(3):171-83. doi: 10.1016/j.molmet.2013.04.004. eCollection 2013. Mol Metab. 2013. PMID: 24049732 Free PMC article.
44 results