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Seralutinib in adults with pulmonary arterial hypertension (TORREY): a randomised, double-blind, placebo-controlled phase 2 trial.
Frantz RP, McLaughlin VV, Sahay S, Escribano Subías P, Zolty RL, Benza RL, Channick RN, Chin KM, Hemnes AR, Howard LS, Sitbon O, Vachiéry JL, Zamanian RT, Cravets M, Roscigno RF, Mottola D, Osterhout R, Bruey JM, Elman E, Tompkins CA, Parsley E, Aranda R, Zisman LS, Ghofrani HA; TORREY Study Investigators. Frantz RP, et al. Among authors: ghofrani ha. Lancet Respir Med. 2024 May 2:S2213-2600(24)00072-9. doi: 10.1016/S2213-2600(24)00072-9. Online ahead of print. Lancet Respir Med. 2024. PMID: 38705167
Microscopic computed tomography with AI-CNN powered image analysis: the path to phenotype the bleomycin-induced pulmonary injury.
Henneke I, Pilz C, Wilhelm J, Alexopoulos I, Ezaddoustdar A, Mukhametshina R, Weissmann N, Ghofrani HA, Grimminger F, Seeger W, Schermuly RT, Wygrecka M, Kojonazarov B. Henneke I, et al. Among authors: ghofrani ha. Am J Physiol Cell Physiol. 2024 Apr 22. doi: 10.1152/ajpcell.00708.2023. Online ahead of print. Am J Physiol Cell Physiol. 2024. PMID: 38646782
Positive Vasoreactivity Testing in Pulmonary Arterial Hypertension: Therapeutic Consequences, Treatment Patterns, and Outcomes in the Modern Management Era.
Gerhardt F, Fiessler E, Olsson KM, Kayser MZ, Kovacs G, Gall H, Ghofrani HA, Badr Eslam R, Lang IM, Benjamin N, Grünig E, Halank M, Lange TJ, Ulrich S, Leuchte H, Held M, Klose H, Ewert R, Wilkens H, Pizarro C, Skowasch D, Wissmüller M, Hellmich M, Olschewski H, Hoeper MM, Rosenkranz S. Gerhardt F, et al. Among authors: ghofrani ha. Circulation. 2024 Apr 12. doi: 10.1161/CIRCULATIONAHA.122.063821. Online ahead of print. Circulation. 2024. PMID: 38606558
Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled study.
Ghofrani HA, Simonneau G, D'Armini AM, Fedullo P, Howard LS, Jaïs X, Jenkins DP, Jing ZC, Madani MM, Martin N, Mayer E, Papadakis K, Richard D, Kim NH; MERIT study investigators. Ghofrani HA, et al. Lancet Respir Med. 2024 Apr;12(4):e21-e30. doi: 10.1016/S2213-2600(24)00027-4. Lancet Respir Med. 2024. PMID: 38548406 Clinical Trial.
Right ventricular pressure-strain relationship-derived myocardial work reflects contractility: Validation with invasive pressure-volume analysis.
Lakatos BK, Rako Z, Szijártó Á, da Rocha BRB, Richter MJ, Fábián A, Gall H, Ghofrani HA, Kremer N, Seeger W, Zedler D, Yildiz S, Yogeswaran A, Merkely B, Tello K, Kovács A. Lakatos BK, et al. Among authors: ghofrani ha. J Heart Lung Transplant. 2024 Mar 18:S1053-2498(24)01532-8. doi: 10.1016/j.healun.2024.03.007. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 38508504 Free article.
Comparison of Contemporary Risk Scores in All Groups of Pulmonary Hypertension: A Pulmonary Vascular Research Institute GoDeep Meta-Registry Analysis.
Yogeswaran A, Gall H, Fünderich M, Wilkins MR, Howard L, Kiely DG, Lawrie A, Hassoun PM, Sirenklo Y, Torbas O, Sweatt AJ, Zamanian RT, Williams PG, Frauendorf M, Arvanitaki A, Giannakoulas G, Saleh K, Sabbour H, Cajigas HR, Frantz R, Al Ghouleh I, Chan SY, Brittain E, Annis JS, Pepe A, Ghio S, Orfanos S, Anthi A, Majeed RW, Wilhelm J, Ghofrani HA, Richter MJ, Grimminger F, Sahay S, Tello K, Seeger W; Pulmonary Vascular Research Institute GoDeep Consortium. Yogeswaran A, et al. Among authors: ghofrani ha. Chest. 2024 Mar 19:S0012-3692(24)00309-X. doi: 10.1016/j.chest.2024.03.018. Online ahead of print. Chest. 2024. PMID: 38508334 Free article.
Liver stiffness is associated with right heart dysfunction, cardiohepatic syndrome, and prognosis in pulmonary hypertension.
Rako ZA, Yogeswaran A, Yildiz S, Weidemann P, Zedler D, da Rocha BB, Kryvenko V, Schäfer S, Ghofrani HA, Seeger W, Kremer NC, Tello K. Rako ZA, et al. Among authors: ghofrani ha. J Heart Lung Transplant. 2024 Feb 17:S1053-2498(24)00056-1. doi: 10.1016/j.healun.2024.02.013. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 38373557 Free article.
Fibroblast growth factor 10 reverses cigarette smoke- and elastase-induced emphysema and pulmonary hypertension in mice.
Hadzic S, Wu CY, Gredic M, Pak O, Loku E, Kraut S, Kojonazarov B, Wilhelm J, Brosien M, Bednorz M, Seimetz M, Günther A, Kosanovic D, Sommer N, Warburton D, Li X, Grimminger F, Ghofrani HA, Schermuly RT, Seeger W, El Agha E, Bellusci S, Weissmann N. Hadzic S, et al. Among authors: ghofrani ha. Eur Respir J. 2023 Nov 9;62(5):2201606. doi: 10.1183/13993003.01606-2022. Print 2023 Nov. Eur Respir J. 2023. PMID: 37884305 Free PMC article.
539 results