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Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice.
Thomas KR, Allenspach EJ, Camp ND, Wray-Dutra MN, Khim S, Zielinska-Kwiatkowska A, Timms AE, Loftus JP, Liggitt HD, Georgopoulos K, Tasian SK, James RG, Rawlings DJ. Thomas KR, et al. Among authors: georgopoulos k. Leukemia. 2022 Jan;36(1):42-57. doi: 10.1038/s41375-021-01326-x. Epub 2021 Jun 30. Leukemia. 2022. PMID: 34193976 Free PMC article.
Ebf1 in DNA repair and leukemogenesis.
Georgopoulos K. Georgopoulos K. Blood. 2015 Jun 25;125(26):3969-71. doi: 10.1182/blood-2015-05-639427. Blood. 2015. PMID: 26113531 Free PMC article.
Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia.
Hu Y, Zhang Z, Kashiwagi M, Yoshida T, Joshi I, Jena N, Somasundaram R, Emmanuel AO, Sigvardsson M, Fitamant J, El-Bardeesy N, Gounari F, Van Etten RA, Georgopoulos K. Hu Y, et al. Among authors: georgopoulos k. Genes Dev. 2016 Sep 1;30(17):1971-90. doi: 10.1101/gad.283762.116. Genes Dev. 2016. PMID: 27664237 Free PMC article.
Transcriptional circuits in B cell transformation.
Hu Y, Yoshida T, Georgopoulos K. Hu Y, et al. Among authors: georgopoulos k. Curr Opin Hematol. 2017 Jul;24(4):345-352. doi: 10.1097/MOH.0000000000000352. Curr Opin Hematol. 2017. PMID: 28463873 Free PMC article. Review.
Chromatin restriction by the nucleosome remodeler Mi-2β and functional interplay with lineage-specific transcription regulators control B-cell differentiation.
Yoshida T, Hu Y, Zhang Z, Emmanuel AO, Galani K, Muhire B, Snippert HJ, Williams CJ, Tolstorukov MY, Gounari F, Georgopoulos K. Yoshida T, et al. Among authors: georgopoulos k. Genes Dev. 2019 Jul 1;33(13-14):763-781. doi: 10.1101/gad.321901.118. Epub 2019 May 23. Genes Dev. 2019. PMID: 31123064 Free PMC article.
A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation.
Lazarian G, Yin S, Ten Hacken E, Sewastianik T, Uduman M, Font-Tello A, Gohil SH, Li S, Kim E, Joyal H, Billington L, Witten E, Zheng M, Huang T, Severgnini M, Lefebvre V, Rassenti LZ, Gutierrez C, Georgopoulos K, Ott CJ, Wang L, Kipps TJ, Burger JA, Livak KJ, Neuberg DS, Baran-Marszak F, Cymbalista F, Carrasco RD, Wu CJ. Lazarian G, et al. Among authors: georgopoulos k. Cancer Cell. 2021 Mar 8;39(3):380-393.e8. doi: 10.1016/j.ccell.2021.02.003. Cancer Cell. 2021. PMID: 33689703 Free PMC article.
114 results