Ebf1 in DNA repair and leukemogenesis

Blood. 2015 Jun 25;125(26):3969-71. doi: 10.1182/blood-2015-05-639427.

Abstract

In this issue of Blood, Prasad et al provide evidence for a new role for the B-lineage transcriptional regulator early B-cell factor 1 (Ebf1) during early B-cell development and B-cell acute lymphoblastic leukemia (B-ALL).

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Transformation, Neoplastic / genetics*
  • DNA Damage / genetics*
  • PAX5 Transcription Factor / genetics*
  • Precursor Cells, B-Lymphoid / metabolism*
  • Trans-Activators / genetics*

Substances

  • PAX5 Transcription Factor
  • Trans-Activators