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Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: genilloud o. Nat Rev Chem. 2021 Oct;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 37118182 Review.
Discovery of bioactive natural products of microbial origin as inhibitors of the PD-1/PD-L1 protein-protein interaction.
Domingo-Contreras E, Tormo JR, Gonzalez-Menendez V, Mackenzie TA, Martín-Serrano J, Magiera-Mularz K, Kitel R, Reyes F, Genilloud O, Fernández-Godino R, Ramos MC, Castillo F. Domingo-Contreras E, et al. Among authors: genilloud o. Int J Biol Macromol. 2024 Apr;264(Pt 1):130458. doi: 10.1016/j.ijbiomac.2024.130458. Epub 2024 Feb 28. Int J Biol Macromol. 2024. PMID: 38423421
Dual targeting of the class V lanthipeptide antibiotic cacaoidin.
Deisinger JP, Arts M, Kotsogianni I, Puls JS, Grein F, Ortiz-López FJ, Martin NI, Müller A, Genilloud O, Schneider T. Deisinger JP, et al. Among authors: genilloud o. iScience. 2023 Mar 11;26(4):106394. doi: 10.1016/j.isci.2023.106394. eCollection 2023 Apr 21. iScience. 2023. PMID: 37013189 Free PMC article.
Evaluation of pro-regenerative and anti-inflammatory effects of isolecanoric acid in the muscle: Potential treatment of Duchenne Muscular Dystrophy.
Matias-Valiente L, Sanchez-Fernandez C, Rodriguez-Outeiriño L, Ramos MC, Díaz C, Crespo G, González-Menéndez V, Genilloud O, Reyes F, Montolio M, Hernandez-Torres F, Aranega AE. Matias-Valiente L, et al. Among authors: genilloud o. Biomed Pharmacother. 2024 Jan;170:116056. doi: 10.1016/j.biopha.2023.116056. Epub 2023 Dec 29. Biomed Pharmacother. 2024. PMID: 38159372 Free article.
Establishment of a screening platform based on human coronavirus OC43 for the identification of microbial natural products with antiviral activity.
Martínez-Arribas B, Annang F, Díaz-González R, Pérez-Moreno G, Martín J, Mackenzie TA, Castillo F, Reyes F, Genilloud O, Ruiz-Pérez LM, Vicente F, Ramos MC, González-Pacanowska D. Martínez-Arribas B, et al. Among authors: genilloud o. Microbiol Spectr. 2024 Jan 11;12(1):e0167923. doi: 10.1128/spectrum.01679-23. Epub 2023 Nov 27. Microbiol Spectr. 2024. PMID: 38009959 Free PMC article.
181 results