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Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
Rueda-Carrasco J, Sokolova D, Lee SE, Childs T, Jurčáková N, Crowley G, De Schepper S, Ge JZ, Lachica JI, Toomey CE, Freeman OJ, Hardy J, Barnes SJ, Lashley T, Stevens B, Chang S, Hong S. Rueda-Carrasco J, et al. Among authors: ge jz. EMBO J. 2023 Oct 4;42(19):e113246. doi: 10.15252/embj.2022113246. Epub 2023 Aug 14. EMBO J. 2023. PMID: 37575021 Free PMC article.
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
De Schepper S, Ge JZ, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin SH, Kim JS, Childs T, Lashley T, Burden JJ, Sasner M, Sala Frigerio C, Jung S, Hong S. De Schepper S, et al. Among authors: ge jz. Nat Neurosci. 2023 Mar;26(3):406-415. doi: 10.1038/s41593-023-01257-z. Epub 2023 Feb 6. Nat Neurosci. 2023. PMID: 36747024 Free PMC article.
31 results