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Effects on molecular conformation and anticoagulant activities of 1,6-anhydrosugars at the reducing terminal of antithrombin-binding octasaccharides isolated from low-molecular-weight heparin enoxaparin.
Guerrini M, Elli S, Gaudesi D, Torri G, Casu B, Mourier P, Herman F, Boudier C, Lorenz M, Viskov C. Guerrini M, et al. Among authors: gaudesi d. J Med Chem. 2010 Nov 25;53(22):8030-40. doi: 10.1021/jm100771s. Epub 2010 Oct 28. J Med Chem. 2010. PMID: 21028827
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Rudd TR, Uniewicz KA, Ori A, Guimond SE, Skidmore MA, Gaudesi D, Xu R, Turnbull JE, Guerrini M, Torri G, Siligardi G, Wilkinson MC, Fernig DG, Yates EA. Rudd TR, et al. Among authors: gaudesi d. Org Biomol Chem. 2010 Dec 7;8(23):5390-7. doi: 10.1039/c0ob00246a. Epub 2010 Sep 3. Org Biomol Chem. 2010. PMID: 20865198
Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution.
Guimond SE, Rudd TR, Skidmore MA, Ori A, Gaudesi D, Cosentino C, Guerrini M, Edge R, Collison D, McInnes E, Torri G, Turnbull JE, Fernig DG, Yates EA. Guimond SE, et al. Among authors: gaudesi d. Biochemistry. 2009 Jun 9;48(22):4772-9. doi: 10.1021/bi802318z. Biochemistry. 2009. PMID: 19400583
15 results