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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 6
2003 3
2004 2
2005 4
2006 5
2007 3
2008 3
2009 2
2010 2
2011 5
2012 7
2013 4
2014 1
2015 1
2016 4
2017 1
2018 3
2019 2
2020 1
2024 0

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55 results

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Page 1
Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin.
N'Guessan K, Grzywa R, Seren S, Gabant G, Juliano MA, Moniatte M, van Dorsselaer A, Bieth JG, Kellenberger C, Gauthier F, Wysocka M, Lesner A, Sienczyk M, Cadene M, Korkmaz B. N'Guessan K, et al. Among authors: gauthier f. FEBS J. 2020 Sep;287(18):4068-4081. doi: 10.1111/febs.15229. Epub 2020 Feb 24. FEBS J. 2020. PMID: 31995266 Free article.
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
Seren S, Rashed Abouzaid M, Eulenberg-Gustavus C, Hirschfeld J, Nasr Soliman H, Jerke U, N'Guessan K, Dallet-Choisy S, Lesner A, Lauritzen C, Schacher B, Eickholz P, Nagy N, Szell M, Croix C, Viaud-Massuard MC, Al Farraj Aldosari A, Ragunatha S, Ibrahim Mostafa M, Giampieri F, Battino M, Cornillier H, Lorette G, Stephan JL, Goizet C, Pedersen J, Gauthier F, Jenne DE, Marchand-Adam S, Chapple IL, Kettritz R, Korkmaz B. Seren S, et al. Among authors: gauthier f. J Biol Chem. 2018 Aug 10;293(32):12415-12428. doi: 10.1074/jbc.RA118.001922. Epub 2018 Jun 20. J Biol Chem. 2018. PMID: 29925593 Free PMC article.
Therapeutic targeting of cathepsin C: from pathophysiology to treatment.
Korkmaz B, Caughey GH, Chapple I, Gauthier F, Hirschfeld J, Jenne DE, Kettritz R, Lalmanach G, Lamort AS, Lauritzen C, Łȩgowska M, Lesner A, Marchand-Adam S, McKaig SJ, Moss C, Pedersen J, Roberts H, Schreiber A, Seren S, Thakker NS. Korkmaz B, et al. Among authors: gauthier f. Pharmacol Ther. 2018 Oct;190:202-236. doi: 10.1016/j.pharmthera.2018.05.011. Epub 2018 May 26. Pharmacol Ther. 2018. PMID: 29842917 Review.
Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.
Guarino C, Gruba N, Grzywa R, Dyguda-Kazimierowicz E, Hamon Y, Łȩgowska M, Skoreński M, Dallet-Choisy S, Marchand-Adam S, Kellenberger C, Jenne DE, Sieńczyk M, Lesner A, Gauthier F, Korkmaz B. Guarino C, et al. Among authors: gauthier f. J Med Chem. 2018 Mar 8;61(5):1858-1870. doi: 10.1021/acs.jmedchem.7b01416. Epub 2018 Feb 26. J Med Chem. 2018. PMID: 29442501
Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.
Guarino C, Hamon Y, Croix C, Lamort AS, Dallet-Choisy S, Marchand-Adam S, Lesner A, Baranek T, Viaud-Massuard MC, Lauritzen C, Pedersen J, Heuzé-Vourc'h N, Si-Tahar M, Fıratlı E, Jenne DE, Gauthier F, Horwitz MS, Borregaard N, Korkmaz B. Guarino C, et al. Among authors: gauthier f. Biochem Pharmacol. 2017 May 1;131:52-67. doi: 10.1016/j.bcp.2017.02.009. Epub 2017 Feb 11. Biochem Pharmacol. 2017. PMID: 28193451
The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection.
Chevaleyre C, Riou M, Bréa D, Vandebrouck C, Barc C, Pezant J, Melo S, Olivier M, Delaunay R, Boulesteix O, Berthon P, Rossignol C, Burlaud Gaillard J, Becq F, Gauthier F, Si-Tahar M, Meurens F, Berri M, Caballero-Posadas I, Attucci S. Chevaleyre C, et al. Among authors: gauthier f. PLoS One. 2016 Dec 16;11(12):e0168577. doi: 10.1371/journal.pone.0168577. eCollection 2016. PLoS One. 2016. PMID: 27992534 Free PMC article.
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
Hamon Y, Legowska M, Hervé V, Dallet-Choisy S, Marchand-Adam S, Vanderlynden L, Demonte M, Williams R, Scott CJ, Si-Tahar M, Heuzé-Vourc'h N, Lalmanach G, Jenne DE, Lesner A, Gauthier F, Korkmaz B. Hamon Y, et al. Among authors: gauthier f. J Biol Chem. 2016 Apr 15;291(16):8486-99. doi: 10.1074/jbc.M115.707109. Epub 2016 Feb 16. J Biol Chem. 2016. PMID: 26884336 Free PMC article.
55 results