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In situ proteolysis for protein crystallization and structure determination.
Dong A, Xu X, Edwards AM; Midwest Center for Structural Genomics; Structural Genomics Consortium; Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, Ignatchenko A, Joachimiak A, Klostermann N, Kim Y, Korniyenko Y, Minor W, Que Q, Savchenko A, Skarina T, Tan K, Yakunin A, Yee A, Yim V, Zhang R, Zheng H, Akutsu M, Arrowsmith C, Avvakumov GV, Bochkarev A, Dahlgren LG, Dhe-Paganon S, Dimov S, Dombrovski L, Finerty P Jr, Flodin S, Flores A, Gräslund S, Hammerström M, Herman MD, Hong BS, Hui R, Johansson I, Liu Y, Nilsson M, Nedyalkova L, Nordlund P, Nyman T, Min J, Ouyang H, Park HW, Qi C, Rabeh W, Shen L, Shen Y, Sukumard D, Tempel W, Tong Y, Tresagues L, Vedadi M, Walker JR, Weigelt J, Welin M, Wu H, Xiao T, Zeng H, Zhu H. Dong A, et al. Among authors: flores a. Nat Methods. 2007 Dec;4(12):1019-21. doi: 10.1038/nmeth1118. Epub 2007 Nov 4. Nat Methods. 2007. PMID: 17982461 Free PMC article.
Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
Lehtiö L, Jemth AS, Collins R, Loseva O, Johansson A, Markova N, Hammarström M, Flores A, Holmberg-Schiavone L, Weigelt J, Helleday T, Schüler H, Karlberg T. Lehtiö L, et al. Among authors: flores a. J Med Chem. 2009 May 14;52(9):3108-11. doi: 10.1021/jm900052j. J Med Chem. 2009. PMID: 19354255
Structure of human argininosuccinate synthetase.
Karlberg T, Collins R, van den Berg S, Flores A, Hammarström M, Högbom M, Holmberg Schiavone L, Uppenberg J. Karlberg T, et al. Among authors: flores a. Acta Crystallogr D Biol Crystallogr. 2008 Mar;64(Pt 3):279-86. doi: 10.1107/S0907444907067455. Epub 2008 Feb 20. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18323623
First structure of a eukaryotic phosphohistidine phosphatase.
Busam RD, Thorsell AG, Flores A, Hammarström M, Persson C, Hallberg BM. Busam RD, et al. Among authors: flores a. J Biol Chem. 2006 Nov 10;281(45):33830-4. doi: 10.1074/jbc.C600231200. Epub 2006 Sep 21. J Biol Chem. 2006. PMID: 16990267 Free article.
1,510 results