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GIPC1 regulates MACC1-driven metastasis.
Siegel F, Schmidt H, Juneja M, Smith J, Herrmann P, Kobelt D, Sharma K, Fichtner I, Walther W, Dittmar G, Volkmer R, Rathjen FG, Schlag PM, Stein U. Siegel F, et al. Among authors: fichtner i. Front Oncol. 2023 Dec 8;13:1280977. doi: 10.3389/fonc.2023.1280977. eCollection 2023. Front Oncol. 2023. PMID: 38144523 Free PMC article.
Establishment and Thorough Characterization of Xenograft (PDX) Models Derived from Patients with Pancreatic Cancer for Molecular Analyses and Chemosensitivity Testing.
Behrens D, Pfohl U, Conrad T, Becker M, Brzezicha B, Büttner B, Wagner S, Hallas C, Lawlor R, Khazak V, Linnebacher M, Wartmann T, Fichtner I, Hoffmann J, Dahlmann M, Walther W. Behrens D, et al. Among authors: fichtner i. Cancers (Basel). 2023 Dec 8;15(24):5753. doi: 10.3390/cancers15245753. Cancers (Basel). 2023. PMID: 38136299 Free PMC article.
Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Alcaniz J, Winkler L, Dahlmann M, Becker M, Orthmann A, Haybaeck J, Krassnig S, Skofler C, Kratzsch T, Kuhn SA, Jödicke A, Linnebacher M, Fichtner I, Walther W, Hoffmann J. Alcaniz J, et al. Among authors: fichtner i. Front Oncol. 2023 Apr 11;13:1129627. doi: 10.3389/fonc.2023.1129627. eCollection 2023. Front Oncol. 2023. PMID: 37114125 Free PMC article.
Author Correction: Loss-of-function uORF mutations in human malignancies.
Schulz J, Mah N, Neuenschwander M, Kischka T, Ratei R, Schlag PM, Castaños-Vélez E, Fichtner I, Tunn PU, Denkert C, Klaas O, Berdel WE, von Kries JP, Makalowski W, Andrade-Navarro MA, Leutz A, Wethmar K. Schulz J, et al. Among authors: fichtner i. Sci Rep. 2021 Jan 28;11(1):2917. doi: 10.1038/s41598-021-82176-6. Sci Rep. 2021. PMID: 33510296 Free PMC article. No abstract available.
Mutation-specific effects of NRAS oncogenes in colorectal cancer cells.
Kuhn N, Klinger B, Uhlitz F, Sieber A, Rivera M, Klotz-Noack K, Fichtner I, Hoffmann J, Blüthgen N, Falk C, Sers C, Schäfer R. Kuhn N, et al. Among authors: fichtner i. Adv Biol Regul. 2021 Jan;79:100778. doi: 10.1016/j.jbior.2020.100778. Epub 2020 Dec 31. Adv Biol Regul. 2021. PMID: 33431353
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine.
Rivera M, Fichtner I, Wulf-Goldenberg A, Sers C, Merk J, Patone G, Alp KM, Kanashova T, Mertins P, Hoffmann J, Stein U, Walther W. Rivera M, et al. Among authors: fichtner i. Neoplasia. 2021 Jan;23(1):21-35. doi: 10.1016/j.neo.2020.11.005. Epub 2020 Nov 16. Neoplasia. 2021. PMID: 33212364 Free PMC article.
Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance.
Grasse S, Lienhard M, Frese S, Kerick M, Steinbach A, Grimm C, Hussong M, Rolff J, Becker M, Dreher F, Schirmer U, Boerno S, Ramisch A, Leschber G, Timmermann B, Grohé C, Lüders H, Vingron M, Fichtner I, Klein S, Odenthal M, Büttner R, Lehrach H, Sültmann H, Herwig R, Schweiger MR. Grasse S, et al. Among authors: fichtner i. Genome Med. 2018 Jul 20;10(1):55. doi: 10.1186/s13073-018-0562-1. Genome Med. 2018. PMID: 30029672 Free PMC article.
Loss-of-function uORF mutations in human malignancies.
Schulz J, Mah N, Neuenschwander M, Kischka T, Ratei R, Schlag PM, Castaños-Vélez E, Fichtner I, Tunn PU, Denkert C, Klaas O, Berdel WE, von Kries JP, Makalowski W, Andrade-Navarro MA, Leutz A, Wethmar K. Schulz J, et al. Among authors: fichtner i. Sci Rep. 2018 Feb 5;8(1):2395. doi: 10.1038/s41598-018-19201-8. Sci Rep. 2018. PMID: 29402903 Free PMC article.
Acquired Resistance of ER-Positive Breast Cancer to Endocrine Treatment Confers an Adaptive Sensitivity to TRAIL through Posttranslational Downregulation of c-FLIP.
Piggott L, Silva A, Robinson T, Santiago-Gómez A, Simões BM, Becker M, Fichtner I, Andera L, Young P, Morris C, Barrett-Lee P, Alchami F, Piva M, Vivanco MD, Clarke RB, Gee J, Clarkson R. Piggott L, et al. Among authors: fichtner i. Clin Cancer Res. 2018 May 15;24(10):2452-2463. doi: 10.1158/1078-0432.CCR-17-1381. Epub 2018 Jan 23. Clin Cancer Res. 2018. PMID: 29363524
223 results