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Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.
Bohlmann L, De Oliveira DMP, El-Deeb IM, Brazel EB, Harbison-Price N, Ong CY, Rivera-Hernandez T, Ferguson SA, Cork AJ, Phan MD, Soderholm AT, Davies MR, Nimmo GR, Dougan G, Schembri MA, Cook GM, McEwan AG, von Itzstein M, McDevitt CA, Walker MJ. Bohlmann L, et al. Among authors: ferguson sa. mBio. 2018 Dec 11;9(6):e02391-18. doi: 10.1128/mBio.02391-18. mBio. 2018. PMID: 30538186 Free PMC article.
Structure of F1-ATPase from the obligate anaerobe Fusobacterium nucleatum.
Petri J, Nakatani Y, Montgomery MG, Ferguson SA, Aragão D, Leslie AGW, Heikal A, Walker JE, Cook GM. Petri J, et al. Among authors: ferguson sa. Open Biol. 2019 Jun 28;9(6):190066. doi: 10.1098/rsob.190066. Epub 2019 Jun 26. Open Biol. 2019. PMID: 31238823 Free PMC article.
Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2.
Harbison-Price N, Ferguson SA, Heikal A, Taiaroa G, Hards K, Nakatani Y, Rennison D, Brimble MA, El-Deeb IM, Bohlmann L, McDevitt CA, von Itzstein M, Walker MJ, Cook GM. Harbison-Price N, et al. Among authors: ferguson sa. mSphere. 2020 Mar 18;5(2):e00157-20. doi: 10.1128/mSphere.00157-20. mSphere. 2020. PMID: 32188750 Free PMC article.
Substituted sulfonamide bioisosteres of 8-hydroxyquinoline as zinc-dependent antibacterial compounds.
McGowan JE, Harper AD, Davison EK, Jeong JY, Mros S, Harbison-Price N, Van Zuylen EM, Knottenbelt MK, Heikal A, Ferguson SA, McConnell MA, Cook GM, Krittaphol W, Walker GF, Brimble MA, Rennison D. McGowan JE, et al. Among authors: ferguson sa. Bioorg Med Chem Lett. 2020 Jun 1;30(11):127110. doi: 10.1016/j.bmcl.2020.127110. Epub 2020 Mar 16. Bioorg Med Chem Lett. 2020. PMID: 32229060
419 results