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Autophagy in healthy aging and disease.
Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF. Aman Y, et al. Among authors: fang ef. Nat Aging. 2021 Aug;1(8):634-650. doi: 10.1038/s43587-021-00098-4. Epub 2021 Aug 12. Nat Aging. 2021. PMID: 34901876 Free PMC article. Review.
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktäschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA. Fang EF, et al. Nat Neurosci. 2019 Mar;22(3):401-412. doi: 10.1038/s41593-018-0332-9. Epub 2019 Feb 11. Nat Neurosci. 2019. PMID: 30742114 Free PMC article.
Mitophagy and Neuroprotection.
Lou G, Palikaras K, Lautrup S, Scheibye-Knudsen M, Tavernarakis N, Fang EF. Lou G, et al. Among authors: fang ef. Trends Mol Med. 2020 Jan;26(1):8-20. doi: 10.1016/j.molmed.2019.07.002. Epub 2019 Jul 30. Trends Mol Med. 2020. PMID: 31375365 Review.
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome.
Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE, Mattson MP, Jasper H, Nilsen H, Bohr VA. Fang EF, et al. Nat Commun. 2019 Nov 21;10(1):5284. doi: 10.1038/s41467-019-13172-8. Nat Commun. 2019. PMID: 31754102 Free PMC article.
Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing.
Gilmour BC, Gudmundsrud R, Frank J, Hov A, Lautrup S, Aman Y, Røsjø H, Brenner C, Ziegler M, Tysnes OB, Tzoulis C, Omland T, Søraas A, Holmøy T, Bergersen LH, Storm-Mathisen J, Nilsen H, Fang EF. Gilmour BC, et al. Among authors: fang ef. Mech Ageing Dev. 2020 Mar;186:111208. doi: 10.1016/j.mad.2020.111208. Epub 2020 Jan 15. Mech Ageing Dev. 2020. PMID: 31953124 Free article. Review.
Culprit or Bystander: Defective Mitophagy in Alzheimer's Disease.
Xie C, Aman Y, Adriaanse BA, Cader MZ, Plun-Favreau H, Xiao J, Fang EF. Xie C, et al. Among authors: fang ef. Front Cell Dev Biol. 2020 Jan 17;7:391. doi: 10.3389/fcell.2019.00391. eCollection 2019. Front Cell Dev Biol. 2020. PMID: 32010698 Free PMC article. Review.
133 results