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N1-guanyl-1,7-diaminoheptane (GC7) enhances the therapeutic efficacy of doxorubicin by inhibiting activation of eukaryotic translation initiation factor 5A2 (eIF5A2) and preventing the epithelial-mesenchymal transition in hepatocellular carcinoma cells.
Lou B, Fan J, Wang K, Chen W, Zhou X, Zhang J, Lin S, Lv F, Chen Y. Lou B, et al. Among authors: fan j. Exp Cell Res. 2013 Oct 15;319(17):2708-17. doi: 10.1016/j.yexcr.2013.08.010. Epub 2013 Aug 16. Exp Cell Res. 2013. PMID: 23958463
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