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HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease.
Romeo MA, Gilardini Montani MS, Gaeta A, D'Orazi G, Faggioni A, Cirone M. Romeo MA, et al. Among authors: faggioni a. Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165647. doi: 10.1016/j.bbadis.2019.165647. Epub 2019 Dec 19. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31866416 Free article.
Kaposi Sarcoma Herpes Virus (KSHV) infection inhibits macrophage formation and survival by counteracting Macrophage Colony-Stimulating Factor (M-CSF)-induced increase of Reactive Oxygen Species (ROS), c-Jun N-terminal kinase (JNK) phosphorylation and autophagy.
Gilardini Montani MS, Falcinelli L, Santarelli R, Romeo MA, Granato M, Faggioni A, Cirone M. Gilardini Montani MS, et al. Among authors: faggioni a. Int J Biochem Cell Biol. 2019 Sep;114:105560. doi: 10.1016/j.biocel.2019.06.008. Epub 2019 Jun 17. Int J Biochem Cell Biol. 2019. PMID: 31220583
187 results