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Proof of concept for a single-dose Group B Streptococcus vaccine based on capsular polysaccharide conjugated to Qβ virus-like particles.
Carboni F, Cozzi R, Romagnoli G, Tuscano G, Balocchi C, Buffi G, Bodini M, Brettoni C, Giusti F, Marchi S, Brogioni G, Brogioni B, Cinelli P, Cappelli L, Nocciolini C, Senesi S, Facciotti C, Frigimelica E, Fabbrini M, Stranges D, Savino S, Maione D, Adamo R, Wizel B, Margarit I, Romano MR. Carboni F, et al. Among authors: facciotti c. NPJ Vaccines. 2023 Oct 6;8(1):152. doi: 10.1038/s41541-023-00744-5. NPJ Vaccines. 2023. PMID: 37803013 Free PMC article.
Author Correction: Proof of concept for a single-dose Group B Streptococcus vaccine based on capsular polysaccharide conjugated to Qβ virus-like particles.
Carboni F, Cozzi R, Romagnoli G, Tuscano G, Balocchi C, Buffi G, Bodini M, Brettoni C, Giusti F, Marchi S, Brogioni G, Brogioni B, Cinelli P, Cappelli L, Nocciolini C, Senesi S, Facciotti C, Frigimelica E, Fabbrini M, Stranges D, Savino S, Maione D, Adamo R, Wizel B, Margarit I, Romano MR. Carboni F, et al. Among authors: facciotti c. NPJ Vaccines. 2024 Jan 25;9(1):19. doi: 10.1038/s41541-024-00808-0. NPJ Vaccines. 2024. PMID: 38272903 Free PMC article. No abstract available.
RrgB321, a fusion protein of the three variants of the pneumococcal pilus backbone RrgB, is protective in vivo and elicits opsonic antibodies.
Harfouche C, Filippini S, Gianfaldoni C, Ruggiero P, Moschioni M, Maccari S, Pancotto L, Arcidiacono L, Galletti B, Censini S, Mori E, Giuliani M, Facciotti C, Cartocci E, Savino S, Doro F, Pallaoro M, Nocadello S, Mancuso G, Haston M, Goldblatt D, Barocchi MA, Pizza M, Rappuoli R, Masignani V. Harfouche C, et al. Among authors: facciotti c. Infect Immun. 2012 Jan;80(1):451-60. doi: 10.1128/IAI.05780-11. Epub 2011 Nov 14. Infect Immun. 2012. PMID: 22083702 Free PMC article.
A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells.
Bagnoli F, Moschioni M, Donati C, Dimitrovska V, Ferlenghi I, Facciotti C, Muzzi A, Giusti F, Emolo C, Sinisi A, Hilleringmann M, Pansegrau W, Censini S, Rappuoli R, Covacci A, Masignani V, Barocchi MA. Bagnoli F, et al. Among authors: facciotti c. J Bacteriol. 2008 Aug;190(15):5480-92. doi: 10.1128/JB.00384-08. Epub 2008 May 30. J Bacteriol. 2008. PMID: 18515415 Free PMC article.
Streptococcus pneumoniae pilus subunits protect mice against lethal challenge.
Gianfaldoni C, Censini S, Hilleringmann M, Moschioni M, Facciotti C, Pansegrau W, Masignani V, Covacci A, Rappuoli R, Barocchi MA, Ruggiero P. Gianfaldoni C, et al. Among authors: facciotti c. Infect Immun. 2007 Feb;75(2):1059-62. doi: 10.1128/IAI.01400-06. Epub 2006 Dec 4. Infect Immun. 2007. PMID: 17145945 Free PMC article.