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Recurrent chromosomal translocations in sarcomas create a megacomplex that mislocalizes NuA4/TIP60 to Polycomb target loci.
Sudarshan D, Avvakumov N, Lalonde ME, Alerasool N, Joly-Beauparlant C, Jacquet K, Mameri A, Lambert JP, Rousseau J, Lachance C, Paquet E, Herrmann L, Thonta Setty S, Loehr J, Bernardini MQ, Rouzbahman M, Gingras AC, Coulombe B, Droit A, Taipale M, Doyon Y, Côté J. Sudarshan D, et al. Genes Dev. 2022 Jun 1;36(11-12):664-683. doi: 10.1101/gad.348982.121. Epub 2022 Jun 16. Genes Dev. 2022. PMID: 35710139 Free PMC article.
MRG Proteins Are Shared by Multiple Protein Complexes With Distinct Functions.
Devoucoux M, Roques C, Lachance C, Lashgari A, Joly-Beauparlant C, Jacquet K, Alerasool N, Prudente A, Taipale M, Droit A, Lambert JP, Hussein SMI, Côté J. Devoucoux M, et al. Mol Cell Proteomics. 2022 Jul;21(7):100253. doi: 10.1016/j.mcpro.2022.100253. Epub 2022 May 28. Mol Cell Proteomics. 2022. PMID: 35636729 Free PMC article.
NuA4 and H2A.Z control environmental responses and autotrophic growth in Arabidopsis.
Bieluszewski T, Sura W, Dziegielewski W, Bieluszewska A, Lachance C, Kabza M, Szymanska-Lejman M, Abram M, Wlodzimierz P, De Winne N, De Jaeger G, Sadowski J, Côté J, Ziolkowski PA. Bieluszewski T, et al. Nat Commun. 2022 Jan 12;13(1):277. doi: 10.1038/s41467-021-27882-5. Nat Commun. 2022. PMID: 35022409 Free PMC article.
De Novo KAT5 Variants Cause a Syndrome with Recognizable Facial Dysmorphisms, Cerebellar Atrophy, Sleep Disturbance, and Epilepsy.
Humbert J, Salian S, Makrythanasis P, Lemire G, Rousseau J, Ehresmann S, Garcia T, Alasiri R, Bottani A, Hanquinet S, Beaver E, Heeley J, Smith ACM, Berger SI, Antonarakis SE, Yang XJ, Côté J, Campeau PM. Humbert J, et al. Am J Hum Genet. 2020 Sep 3;107(3):564-574. doi: 10.1016/j.ajhg.2020.08.002. Epub 2020 Aug 20. Am J Hum Genet. 2020. PMID: 32822602 Free PMC article.
16 results