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2016 1
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2018 3
2019 1
2021 2
2022 2
2024 0

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Page 1
Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor.
Kleist AB, Jenjak S, Sente A, Laskowski LJ, Szpakowska M, Calkins MM, Anderson EI, McNally LM, Heukers R, Bobkov V, Peterson FC, Thomas MA, Chevigné A, Smit MJ, McCorvy JD, Babu MM, Volkman BF. Kleist AB, et al. Science. 2022 Jul 8;377(6602):222-228. doi: 10.1126/science.abj4922. Epub 2022 Jul 7. Science. 2022. PMID: 35857540 Free PMC article.
CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk.
Baer C, Kimura S, Rana MS, Kleist AB, Flerlage T, Feith DJ, Chockley P, Walter W, Meggendorfer M, Olson TL, Cheon H, Olson KC, Ratan A, Mueller ML, Foran JM, Janke LJ, Qu C, Porter SN, Pruett-Miller SM, Kalathur RC, Haferlach C, Kern W, Paietta E, Thomas PG, Babu MM, Loughran TP Jr, Iacobucci I, Haferlach T, Mullighan CG. Baer C, et al. Nat Genet. 2022 May;54(5):637-648. doi: 10.1038/s41588-022-01059-2. Epub 2022 May 5. Nat Genet. 2022. PMID: 35513723 Free PMC article.
Evolution of fold switching in a metamorphic protein.
Dishman AF, Tyler RC, Fox JC, Kleist AB, Prehoda KE, Babu MM, Peterson FC, Volkman BF. Dishman AF, et al. Science. 2021 Jan 1;371(6524):86-90. doi: 10.1126/science.abd8700. Science. 2021. PMID: 33384377 Free PMC article.
Decoding the chemotactic signal.
Thomas MA, Kleist AB, Volkman BF. Thomas MA, et al. J Leukoc Biol. 2018 Aug;104(2):359-374. doi: 10.1002/JLB.1MR0218-044. Epub 2018 Jun 6. J Leukoc Biol. 2018. PMID: 29873835 Free PMC article. Review.
Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3.
Szpakowska M, Nevins AM, Meyrath M, Rhainds D, D'huys T, Guité-Vinet F, Dupuis N, Gauthier PA, Counson M, Kleist A, St-Onge G, Hanson J, Schols D, Volkman BF, Heveker N, Chevigné A. Szpakowska M, et al. Br J Pharmacol. 2018 May;175(9):1419-1438. doi: 10.1111/bph.14132. Epub 2018 Mar 23. Br J Pharmacol. 2018. PMID: 29272550 Free PMC article.
Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.
Ziarek JJ, Kleist AB, London N, Raveh B, Montpas N, Bonneterre J, St-Onge G, DiCosmo-Ponticello CJ, Koplinski CA, Roy I, Stephens B, Thelen S, Veldkamp CT, Coffman FD, Cohen MC, Dwinell MB, Thelen M, Peterson FC, Heveker N, Volkman BF. Ziarek JJ, et al. Sci Signal. 2017 Mar 21;10(471):eaah5756. doi: 10.1126/scisignal.aah5756. Sci Signal. 2017. PMID: 28325822 Free PMC article.