Erciyas E - Search Results

1

1,4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood-brain barrier.

Prinz M, Parlar S, Bayraktar G, Alptüzün V, Erciyas E, Fallarero A, Karlsson D, Vuorela P, Burek M, Förster C, Turunc E, Armagan G, Yalcin A, Schiller C, Leuner K, Krug M, Sotriffer CA, Holzgrabe U. Prinz M, et al. Among authors: erciyas e. Eur J Pharm Sci. 2013 Jul 16;49(4):603-13. doi: 10.1016/j.ejps.2013.04.024. Epub 2013 May 2. Eur J Pharm Sci. 2013. PMID: 23643737

2

[Synthesis and stereochemistry of potentially powerful analgesics: 2,4-m-diaryl substituted 3,7-diazabicyclo(3,3,1)nonan-9-one-1,5-diesters].

Holzgrabe U, Erciyas E. Holzgrabe U, et al. Among authors: erciyas e. Arch Pharm (Weinheim). 1992 Oct;325(10):657-63. doi: 10.1002/ardp.19923251008. Arch Pharm (Weinheim). 1992. PMID: 1334646 German.

3

Cooperative interactions at M2 muscarinic acetylcholine receptors: structure/activity relationships in stepwise shortened bispyridinium- and bis(ammonio)alkane-type allosteric modulators.

Gilsbach R, Grossmüller M, Alptüzün V, Erciyas E, Tränkle C, Holzgrabe U, Mohr K. Gilsbach R, et al. Among authors: erciyas e. Neurochem Res. 2003 Apr;28(3-4):667-73. doi: 10.1023/a:1022858414900. Neurochem Res. 2003. PMID: 12675159

4

Synthesis and biological activity of pyridinium-type acetylcholinesterase inhibitors.

Alptüzün V, Kapková P, Baumann K, Erciyas E, Holzgrabe U. Alptüzün V, et al. Among authors: erciyas e. J Pharm Pharmacol. 2003 Oct;55(10):1397-404. doi: 10.1211/0022357021855. J Pharm Pharmacol. 2003. PMID: 14607022

5

Search for dual function inhibitors for Alzheimer's disease: synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Abeta fibril formation inhibition capacity.

Kapková P, Alptüzün V, Frey P, Erciyas E, Holzgrabe U. Kapková P, et al. Among authors: erciyas e. Bioorg Med Chem. 2006 Jan 15;14(2):472-8. doi: 10.1016/j.bmc.2005.08.034. Epub 2005 Sep 29. Bioorg Med Chem. 2006. PMID: 16198581

The most explored recent approaches that are closely related to the pathogenesis of this disease based on formally articulated amyloid hypothesis are: Abeta fibril formation inhibitors, amyloid precursor protein, and secretase inhibitors. [Scarpini, E.; Scheltens, P.; Feld …

The most explored recent approaches that are closely related to the pathogenesis of this disease based on formally articulated amyloid hypot …

6

Synthesis and antimicrobial activity of some pyridinium salts.

Alptüzün V, Parlar S, Taşli H, Erciyas E. Alptüzün V, et al. Among authors: erciyas e. Molecules. 2009 Dec 14;14(12):5203-15. doi: 10.3390/molecules14125203. Molecules. 2009. PMID: 20032886 Free PMC article.

7

Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases.

Alptüzün V, Prinz M, Hörr V, Scheiber J, Radacki K, Fallarero A, Vuorela P, Engels B, Braunschweig H, Erciyas E, Holzgrabe U. Alptüzün V, et al. Among authors: erciyas e. Bioorg Med Chem. 2010 Mar 1;18(5):2049-59. doi: 10.1016/j.bmc.2010.01.002. Epub 2010 Jan 15. Bioorg Med Chem. 2010. PMID: 20149667

8

Synthesis and antileishmanial activity of novel pyridinium-hydrazone derivatives.

Alptuzun V, Cakiroglu G, Limoncu ME, Erac B, Hosgor-Limoncu M, Erciyas E. Alptuzun V, et al. Among authors: erciyas e. J Enzyme Inhib Med Chem. 2013 Oct;28(5):960-7. doi: 10.3109/14756366.2012.697058. Epub 2012 Jul 18. J Enzyme Inhib Med Chem. 2013. PMID: 22803671

9

Synthesis, Biological Evaluation and Molecular Docking Study of Hydrazone-Containing Pyridinium Salts as Cholinesterase Inhibitors.

Parlar S, Bayraktar G, Tarikogullari AH, Alptüzün V, Erciyas E. Parlar S, et al. Among authors: erciyas e. Chem Pharm Bull (Tokyo). 2016;64(9):1281-7. doi: 10.1248/cpb.c16-00221. Chem Pharm Bull (Tokyo). 2016. PMID: 27581632 Free article.

10

Synthesis and evaluation of pyridinium-hydrazone derivatives as potential antitumoral agents.

Parlar S, Erzurumlu Y, Ilhan R, Ballar Kırmızıbayrak P, Alptüzün V, Erciyas E. Parlar S, et al. Among authors: erciyas e. Chem Biol Drug Des. 2018 Jul;92(1):1198-1205. doi: 10.1111/cbdd.13177. Epub 2018 Mar 13. Chem Biol Drug Des. 2018. PMID: 29415336

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