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Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17.
Moreno-Càceres J, Caja L, Mainez J, Mayoral R, Martín-Sanz P, Moreno-Vicente R, Del Pozo MÁ, Dooley S, Egea G, Fabregat I. Moreno-Càceres J, et al. Among authors: egea g. Cell Death Dis. 2014 Jul 17;5(7):e1326. doi: 10.1038/cddis.2014.294. Cell Death Dis. 2014. PMID: 25032849 Free PMC article.
Vascular smooth muscle cell phenotypic changes in patients with Marfan syndrome.
Crosas-Molist E, Meirelles T, López-Luque J, Serra-Peinado C, Selva J, Caja L, Gorbenko Del Blanco D, Uriarte JJ, Bertran E, Mendizábal Y, Hernández V, García-Calero C, Busnadiego O, Condom E, Toral D, Castellà M, Forteza A, Navajas D, Sarri E, Rodríguez-Pascual F, Dietz HC, Fabregat I, Egea G. Crosas-Molist E, et al. Among authors: egea g. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):960-72. doi: 10.1161/ATVBAHA.114.304412. Epub 2015 Jan 15. Arterioscler Thromb Vasc Biol. 2015. PMID: 25593132
Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm.
Jiménez-Altayó F, Meirelles T, Crosas-Molist E, Sorolla MA, Del Blanco DG, López-Luque J, Mas-Stachurska A, Siegert AM, Bonorino F, Barberà L, García C, Condom E, Sitges M, Rodríguez-Pascual F, Laurindo F, Schröder K, Ros J, Fabregat I, Egea G. Jiménez-Altayó F, et al. Among authors: egea g. Free Radic Biol Med. 2018 Apr;118:44-58. doi: 10.1016/j.freeradbiomed.2018.02.023. Epub 2018 Feb 20. Free Radic Biol Med. 2018. PMID: 29471108
Anti-TGFβ (Transforming Growth Factor β) Therapy With Betaglycan-Derived P144 Peptide Gene Delivery Prevents the Formation of Aortic Aneurysm in a Mouse Model of Marfan Syndrome.
Arce C, Rodríguez-Rovira I, De Rycke K, Durán K, Campuzano V, Fabregat I, Jiménez-Altayó F, Berraondo P, Egea G. Arce C, et al. Among authors: egea g. Arterioscler Thromb Vasc Biol. 2021 Sep;41(9):e440-e452. doi: 10.1161/ATVBAHA.121.316496. Epub 2021 Jun 24. Arterioscler Thromb Vasc Biol. 2021. PMID: 34162229 Free article.
133 results