Duggan S - Search Results

1

Inflammation and esophageal carcinogenesis.

Abdel-Latif MM, Duggan S, Reynolds JV, Kelleher D. Abdel-Latif MM, et al. Among authors: duggan s. Curr Opin Pharmacol. 2009 Aug;9(4):396-404. doi: 10.1016/j.coph.2009.06.010. Epub 2009 Jul 10. Curr Opin Pharmacol. 2009. PMID: 19596608 Review.

2

Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells.

Looby E, Abdel-Latif MM, Athié-Morales V, Duggan S, Long A, Kelleher D. Looby E, et al. Among authors: duggan s. BMC Cancer. 2009 Jun 17;9:190. doi: 10.1186/1471-2407-9-190. BMC Cancer. 2009. PMID: 19534809 Free PMC article.

3

Low pH induces co-ordinate regulation of gene expression in oesophageal cells.

Duggan SP, Gallagher WM, Fox EJ, Abdel-Latif MM, Reynolds JV, Kelleher D. Duggan SP, et al. Carcinogenesis. 2006 Feb;27(2):319-27. doi: 10.1093/carcin/bgi211. Epub 2005 Aug 19. Carcinogenesis. 2006. PMID: 16113055

4

Inherited Syndromes Predisposing to Inflammation and GI Cancer.

Duggan S, Prichard D, Kirca M, Kelleher D. Duggan S, et al. Recent Results Cancer Res. 2011;185:35-50. doi: 10.1007/978-3-642-03503-6_2. Recent Results Cancer Res. 2011. PMID: 21822818 Review.

5

Gene expression analysis of diagnostic biopsies predicts pathological response to neoadjuvant chemoradiotherapy of esophageal cancer.

Maher SG, Gillham CM, Duggan SP, Smyth PC, Miller N, Muldoon C, O'Byrne KJ, Sheils OM, Hollywood D, Reynolds JV. Maher SG, et al. Ann Surg. 2009 Nov;250(5):729-37. doi: 10.1097/SLA.0b013e3181bce7e1. Ann Surg. 2009. PMID: 19801928

6

An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-kappaB activation and cytokine levels.

Duggan SP, Behan FM, Kirca M, Smith S, Reynolds JV, Long A, Kelleher D. Duggan SP, et al. Carcinogenesis. 2010 May;31(5):936-45. doi: 10.1093/carcin/bgq036. Epub 2010 Feb 5. Carcinogenesis. 2010. PMID: 20139130

7

The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.

Duggan SP, Behan FM, Kirca M, Zaheer A, McGarrigle SA, Reynolds JV, Vaz GM, Senge MO, Kelleher D. Duggan SP, et al. Sci Rep. 2016 Sep 2;6:32638. doi: 10.1038/srep32638. Sci Rep. 2016. PMID: 27586588 Free PMC article.

8

siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth.

Duggan SP, Garry C, Behan FM, Phipps S, Kudo H, Kirca M, Zaheer A, McGarrigle S, Reynolds JV, Goldin R, Kalloger SE, Schaeffer DF, Long A, Strid J, Kelleher D. Duggan SP, et al. Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):569-590. doi: 10.1016/j.jcmgh.2018.01.012. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 29930979 Free PMC article.

9

High Content Imaging of Barrett's-Associated High-Grade Dysplasia Cells After siRNA Library Screening Reveals Acid-Responsive Regulators of Cellular Transitions.

Phipps SM, Garry CE, Kamal S, Johnson JD, Gilmer J, Long A, Kelleher D, Duggan SP. Phipps SM, et al. Among authors: duggan sp. Cell Mol Gastroenterol Hepatol. 2020;10(3):601-622. doi: 10.1016/j.jcmgh.2020.05.002. Epub 2020 May 13. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32416156 Free PMC article.

10

The Immune Underpinnings of Barrett's-Associated Adenocarcinogenesis: a Retrial of Nefarious Immunologic Co-Conspirators.

Tambunting L, Kelleher D, Duggan SP. Tambunting L, et al. Cell Mol Gastroenterol Hepatol. 2022;13(5):1297-1315. doi: 10.1016/j.jcmgh.2022.01.023. Epub 2022 Feb 3. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35123116 Free PMC article. Review.

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