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A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.
Yu X, Ma H, Li B, Ji Y, Du Y, Liu S, Li Z, Hao Y, Tian S, Zhao C, Du Q, Jin Z, Zhu X, Tian Y, Chen X, Sun X, Yang C, Zhu F, Ju J, Zheng Y, Zhang W, Wang J, Yang T, Wang X, Li J, Xu X, Du S, Lu H, Ma F, Zhang H, Zhang Y, Zhang X, Hu S, He S. Yu X, et al. Among authors: du y, du s, du q. Blood. 2023 Mar 2;141(9):1070-1086. doi: 10.1182/blood.2022017262. Blood. 2023. PMID: 36356302 Free PMC article.
Structural optimization of aminopyrimidine-based CXCR4 antagonists.
Zhu F, Wang Y, Du Q, Ge W, Li Z, Wang X, Fu C, Luo L, Tian S, Ma H, Zheng J, Zhang Y, Sun X, He S, Zhang X. Zhu F, et al. Among authors: du q. Eur J Med Chem. 2020 Feb 1;187:111914. doi: 10.1016/j.ejmech.2019.111914. Epub 2019 Nov 26. Eur J Med Chem. 2020. PMID: 31806538
Menthone inhibits type-I interferon signaling by promoting Tyk2 ubiquitination to relieve local inflammation of rheumatoid arthritis.
Chen X, Wu Q, Cao X, Yang Y, Gong Z, Ren T, Du Q, Yuan Y, Zuo Y, Miao Y, He J, Qiao C, Zheng Z, Zhang T, Xu Y, Wu D, Wang Q, Huang L, Xie Z, Lv H, Wang J, Gong F, Liu Z, Wen C, Zheng H. Chen X, et al. Among authors: du q. Int Immunopharmacol. 2022 Nov;112:109228. doi: 10.1016/j.intimp.2022.109228. Epub 2022 Sep 9. Int Immunopharmacol. 2022. PMID: 36095947
A Natural Plant Ingredient, Menthone, Regulates T Cell Subtypes and Lowers Pro-inflammatory Cytokines of Rheumatoid Arthritis.
Chen X, Wu Q, Gong Z, Ren T, Du Q, Yuan Y, Zuo Y, Miao Y, He J, Qiao C, Zheng Z, Zhang T, Huang L, Xie Z, Wang J, Zhu Y, Zhu C, Xu Y, Wu D, Gong F, Cheng J, Wen C, Zheng H. Chen X, et al. Among authors: du q. J Nat Prod. 2022 Apr 22;85(4):1109-1117. doi: 10.1021/acs.jnatprod.1c01231. Epub 2022 Mar 18. J Nat Prod. 2022. PMID: 35302365 Review.
Cycloheximide (CHX) Chase Assay to Examine Protein Half-life.
Miao Y, Du Q, Zhang HG, Yuan Y, Zuo Y, Zheng H. Miao Y, et al. Among authors: du q. Bio Protoc. 2023 Jun 5;13(11):e4690. doi: 10.21769/BioProtoc.4690. eCollection 2023 Jun 5. Bio Protoc. 2023. PMID: 37323633 Free PMC article.
3,413 results