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A five-day treatment course of zanamivir for the flu with a single, self-administered, painless microneedle array patch: Revolutionizing delivery of poorly membrane-permeable therapeutics.
Reyna D, Bejster I, Chadderdon A, Harteg C, Kurnia Anjani Q, Hidayat Bin Sabri A, Brown AN, Drusano GL, Westover J, Bart Tarbet E, Vora LK, Donnelly RF, Lipka E. Reyna D, et al. Among authors: drusano gl. Int J Pharm. 2023 Jun 25;641:123081. doi: 10.1016/j.ijpharm.2023.123081. Epub 2023 May 23. Int J Pharm. 2023. PMID: 37230371
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models.
Jiao Y, Yan J, Sutaria DS, Lu P, Vicchiarelli M, Reyna Z, Ruiz-Delgado J, Burk E, Moon E, Shah NR, Spellberg B, Bonomo RA, Drusano GL, Louie A, Luna BM, Bulitta JB. Jiao Y, et al. Among authors: drusano gl. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0139423. doi: 10.1128/aac.01394-23. Epub 2024 Jan 30. Antimicrob Agents Chemother. 2024. PMID: 38289076 Free PMC article.
Correction: 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-β-lactamases.
Rossi MA, Martinez V, Hinchliffe P, Mojica MF, Castillo V, Moreno DM, Smith R, Spellberg B, Drusano GL, Banchio C, Bonomo RA, Spencer J, Vila AJ, Mahler G. Rossi MA, et al. Among authors: drusano gl. Chem Sci. 2023 Aug 15;14(34):9226. doi: 10.1039/d3sc90150e. eCollection 2023 Aug 30. Chem Sci. 2023. PMID: 37655038 Free PMC article.
Individual Components of Polymyxin B Modeled via Population Pharmacokinetics to Design Humanized Dosage Regimens for a Bloodstream and Lung Infection Model in Immune-Competent Mice.
Jiao Y, Yan J, Vicchiarelli M, Sutaria DS, Lu P, Reyna Z, Spellberg B, Bonomo RA, Drusano GL, Louie A, Luna BM, Bulitta JB. Jiao Y, et al. Among authors: drusano gl. Antimicrob Agents Chemother. 2023 May 17;67(5):e0019723. doi: 10.1128/aac.00197-23. Epub 2023 Apr 6. Antimicrob Agents Chemother. 2023. PMID: 37022153 Free PMC article.
Why Molnupiravir Fails in Hospitalized Patients.
Brown AN, Lang Y, Zhou J, Franco EJ, Hanrahan KC, Bulitta JB, Drusano GL. Brown AN, et al. Among authors: drusano gl. mBio. 2022 Dec 20;13(6):e0291622. doi: 10.1128/mbio.02916-22. Epub 2022 Nov 14. mBio. 2022. PMID: 36374076 Free PMC article.
Evaluating the effect of clofazimine against Mycobacterium tuberculosis given alone or in combination with pretomanid, bedaquiline or linezolid.
Kim S, Louie A, Drusano GL, Almoslem M, Kim S, Myrick J, Nole J, Duncanson B, Peloquin CA, Scanga CA, Yamada W, Neely M, Schmidt S. Kim S, et al. Among authors: drusano gl. Int J Antimicrob Agents. 2022 Feb;59(2):106509. doi: 10.1016/j.ijantimicag.2021.106509. Epub 2021 Dec 25. Int J Antimicrob Agents. 2022. PMID: 34958863
347 results