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Page 1
CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells.
Kim MC, Borcherding N, Ahmed KK, Voigt AP, Vishwakarma A, Kolb R, Kluz PN, Pandey G, De U, Drashansky T, Helm EY, Zhang X, Gibson-Corley KN, Klesney-Tait J, Zhu Y, Lu J, Lu J, Huang X, Xiang H, Cheng J, Wang D, Wang Z, Tang J, Hu J, Wang Z, Liu H, Li M, Zhuang H, Avram D, Zhou D, Bacher R, Zheng SG, Wu X, Zakharia Y, Zhang W. Kim MC, et al. Among authors: drashansky t. Nat Commun. 2021 Oct 1;12(1):5764. doi: 10.1038/s41467-021-26091-4. Nat Commun. 2021. PMID: 34599187 Free PMC article.
Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation.
Cho JJ, Xu Z, Parthasarathy U, Drashansky TT, Helm EY, Zuniga AN, Lorentsen KJ, Mansouri S, Cho JY, Edelmann MJ, Duong DM, Gehring T, Seeholzer T, Krappmann D, Uddin MN, Califano D, Wang RL, Jin L, Li H, Lv D, Zhou D, Zhou L, Avram D. Cho JJ, et al. Among authors: drashansky tt. Nat Commun. 2019 Feb 11;10(1):701. doi: 10.1038/s41467-019-08605-3. Nat Commun. 2019. PMID: 30741923 Free PMC article.
The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation.
Holmes TD, Pandey RV, Helm EY, Schlums H, Han H, Campbell TM, Drashansky TT, Chiang S, Wu CY, Tao C, Shoukier M, Tolosa E, Von Hardenberg S, Sun M, Klemann C, Marsh RA, Lau CM, Lin Y, Sun JC, Månsson R, Cichocki F, Avram D, Bryceson YT. Holmes TD, et al. Among authors: drashansky tt. Sci Immunol. 2021 Mar 12;6(57):eabc9801. doi: 10.1126/sciimmunol.abc9801. Sci Immunol. 2021. PMID: 33712472 Free PMC article.
BCL11B is positioned upstream of PLZF and RORγt to control thymic development of mucosal-associated invariant T cells and MAIT17 program.
Drashansky TT, Helm EY, Curkovic N, Cooper J, Cheng P, Chen X, Gautam N, Meng L, Kwiatkowski AJ, Collins WO, Keselowsky BG, Sant'Angelo D, Huo Z, Zhang W, Zhou L, Avram D. Drashansky TT, et al. iScience. 2021 Mar 13;24(4):102307. doi: 10.1016/j.isci.2021.102307. eCollection 2021 Apr 23. iScience. 2021. PMID: 33870128 Free PMC article.
An antigen-specific semi-therapeutic treatment with local delivery of tolerogenic factors through a dual-sized microparticle system blocks experimental autoimmune encephalomyelitis.
Cho JJ, Stewart JM, Drashansky TT, Brusko MA, Zuniga AN, Lorentsen KJ, Keselowsky BG, Avram D. Cho JJ, et al. Among authors: drashansky tt. Biomaterials. 2017 Oct;143:79-92. doi: 10.1016/j.biomaterials.2017.07.029. Epub 2017 Jul 24. Biomaterials. 2017. PMID: 28772190 Free PMC article.
Placental circulating T cells: a novel, allogeneic CAR-T cell platform with preserved T-cell stemness, more favorable cytokine profile, and durable efficacy compared to adult PBMC-derived CAR-T.
Ruggeri Barbaro N, Drashansky T, Tess K, Djedaini M, Hariri R, He S, van der Touw W, Karasiewicz K. Ruggeri Barbaro N, et al. Among authors: drashansky t. J Immunother Cancer. 2024 Apr 29;12(4):e008656. doi: 10.1136/jitc-2023-008656. J Immunother Cancer. 2024. PMID: 38684370 Free article.
Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8+ T cells.
Helm EY, Zelenka T, Cismasiu VB, Islam S, Silvane L, Zitti B, Holmes TD, Drashansky TT, Kwiatkowski AJ, Tao C, Dean J, Obermayer AN, Chen X, Keselowsky BG, Zhang W, Huo Z, Zhou L, Sheridan BS, Conejo-Garcia JR, Shaw TI, Bryceson YT, Avram D. Helm EY, et al. Among authors: drashansky tt. Sci Immunol. 2023 Apr 28;8(82):eabn0484. doi: 10.1126/sciimmunol.abn0484. Epub 2023 Apr 28. Sci Immunol. 2023. PMID: 37115913 Free PMC article.
11 results