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Discovery and Synthesis of C-Nucleosides as Potential New Anti-HCV Agents.
ACS Med Chem Lett. 2014 Apr 10;5(6):679-84. doi: 10.1021/ml500077j. eCollection 2014 Jun 12.
ACS Med Chem Lett. 2014.
PMID: 24944743
Free PMC article.
Derivatives of imidazotriazine and pyrrolotriazine C-nucleosides as potential new anti-HCV agents.
Draffan AG, Frey B, Fraser BH, Pool B, Gannon C, Tyndall EM, Cianci J, Harding M, Lilly M, Hufton R, Halim R, Jahangiri S, Bond S, Jeynes TP, Nguyen VT, Wirth V, Luttick A, Tilmanis D, Pryor M, Porter K, Morton CJ, Lin B, Duan J, Bethell RC, Kukolj G, Simoneau B, Tucker SP.
Draffan AG, et al.
Bioorg Med Chem Lett. 2014 Nov 1;24(21):4984-8. doi: 10.1016/j.bmcl.2014.09.030. Epub 2014 Sep 21.
Bioorg Med Chem Lett. 2014.
PMID: 25288185
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Prodrugs of imidazotriazine and pyrrolotriazine C-nucleosides can increase anti-HCV activity and enhance nucleotide triphosphate concentrations in vitro.
Tyndall EM, Draffan AG, Frey B, Pool B, Halim R, Jahangiri S, Bond S, Wirth V, Luttick A, Tilmanis D, Thomas J, Porter K, Tucker SP.
Tyndall EM, et al. Among authors: draffan ag.
Bioorg Med Chem Lett. 2015 Feb 15;25(4):869-73. doi: 10.1016/j.bmcl.2014.12.069. Epub 2014 Dec 30.
Bioorg Med Chem Lett. 2015.
PMID: 25592710
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The discovery of 1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-ones as a new class of respiratory syncytial virus (RSV) fusion inhibitors. Part 1.
Bond S, Draffan AG, Fenner JE, Lambert J, Lim CY, Lin B, Luttick A, Mitchell JP, Morton CJ, Nearn RH, Sanford V, Stanislawski PC, Tucker SP.
Bond S, et al. Among authors: draffan ag.
Bioorg Med Chem Lett. 2015 Feb 15;25(4):969-75. doi: 10.1016/j.bmcl.2014.11.018. Epub 2014 Nov 15.
Bioorg Med Chem Lett. 2015.
PMID: 25595682
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1,2,3,9b-Tetrahydro-5H-imidazo[2,1-a]isoindol-5-ones as a new class of respiratory syncytial virus (RSV) fusion inhibitors. Part 2: identification of BTA9881 as a preclinical candidate.
Bond S, Draffan AG, Fenner JE, Lambert J, Lim CY, Lin B, Luttick A, Mitchell JP, Morton CJ, Nearn RH, Sanford V, Anderson KH, Mayes PA, Tucker SP.
Bond S, et al. Among authors: draffan ag.
Bioorg Med Chem Lett. 2015 Feb 15;25(4):976-81. doi: 10.1016/j.bmcl.2014.11.024. Epub 2014 Nov 14.
Bioorg Med Chem Lett. 2015.
PMID: 25595685
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A chemoenzymatic and fully stereocontrolled total synthesis of the antibacterial natural product (-)-platencin.
Chang EL, Schwartz BD, Draffan AG, Banwell MG, Willis AC.
Chang EL, et al. Among authors: draffan ag.
Chem Asian J. 2015 Feb;10(2):427-39. doi: 10.1002/asia.201403069. Epub 2014 Nov 13.
Chem Asian J. 2015.
PMID: 25393231
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Light-induced Enzyme Formation in a Chlorophyll-less Mutant of Euglena gracilis.
Russell GK, Draffan AG.
Russell GK, et al. Among authors: draffan ag.
Plant Physiol. 1978 Nov;62(5):678-82. doi: 10.1104/pp.62.5.678.
Plant Physiol. 1978.
PMID: 16660582
Free PMC article.
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