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(S)-(+)-4-[7-(2,2-dimethyl-1-oxopropoxy)-4-methyl-2-[4-[2-(1-piperidinyl)-ethoxy]phenyl]-2H-1-benzopyran-3-yl]-phenyl 2,2-dimethylpropanoate (EM-800): a highly potent, specific, and orally active nonsteroidal antiestrogen.
Gauthier S, Caron B, Cloutier J, Dory YL, Favre A, Larouche D, Mailhot J, Ouellet C, Schwerdtfeger A, Leblanc G, Martel C, Simard J, Mérand Y, Bélanger A, Labrie C, Labrie F. Gauthier S, et al. Among authors: dory yl. J Med Chem. 1997 Jul 4;40(14):2117-22. doi: 10.1021/jm970095o. J Med Chem. 1997. PMID: 9216828 No abstract available.
Efficient parallel synthesis of macrocyclic peptidomimetics.
Marsault E, Hoveyda HR, Gagnon R, Peterson ML, Vézina M, Saint-Louis C, Landry A, Pinault JF, Ouellet L, Beauchemin S, Beaubien S, Mathieu A, Benakli K, Wang Z, Brassard M, Lonergan D, Bilodeau F, Ramaseshan M, Fortin N, Lan R, Li S, Galaud F, Plourde V, Champagne M, Doucet A, Bhérer P, Gauthier M, Olsen G, Villeneuve G, Bhat S, Foucher L, Fortin D, Peng X, Bernard S, Drouin A, Déziel R, Berthiaume G, Dory YL, Fraser GL, Deslongchamps P. Marsault E, et al. Among authors: dory yl. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4731-5. doi: 10.1016/j.bmcl.2008.06.085. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18640834
High throughput solid phase parallel synthesis of macrocyclic peptidomimetics.
Marsault E, Hoveyda HR, Peterson ML, Gagnon R, Vézina M, Pinault JF, Landry A, Saint-Louis C, Ouellet LG, Beauchemin S, Benakli K, Beaubien S, Brassard M, Wang Z, Champagne M, Galaud F, Fortin N, Fortin D, Plourde V, Ramaseshan M, Bhat S, Bilodeau F, Lonergan D, Lan R, Li S, Berthiaume G, Foucher L, Peng X, Dory Y, Deslongchamps P. Marsault E, et al. Adv Exp Med Biol. 2009;611:15-6. doi: 10.1007/978-0-387-73657-0_7. Adv Exp Med Biol. 2009. PMID: 19400074 No abstract available.
The Multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cells.
Levesque C, Fugère M, Kwiatkowska A, Couture F, Desjardins R, Routhier S, Moussette P, Prahl A, Lammek B, Appel JR, Houghten RA, D'Anjou F, Dory YL, Neugebauer W, Day R. Levesque C, et al. Among authors: dory yl. J Med Chem. 2012 Dec 13;55(23):10501-11. doi: 10.1021/jm3011178. Epub 2012 Nov 14. J Med Chem. 2012. PMID: 23126600 Free PMC article.
Therapeutic uses of furin and its inhibitors: a patent review.
Couture F, Kwiatkowska A, Dory YL, Day R. Couture F, et al. Among authors: dory yl. Expert Opin Ther Pat. 2015 Apr;25(4):379-96. doi: 10.1517/13543776.2014.1000303. Epub 2015 Jan 7. Expert Opin Ther Pat. 2015. PMID: 25563687 Review.
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