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A New Protocol for the Synthesis of New Thioaryl-Porphyrins Derived from 5,10,15,20-Tetrakis(pentafluorophenyl)porphyrin: Photophysical Evaluation and DNA-Binding Interactive Studies.
Foletto P, Correa F, Dornelles L, A Iglesias B, H da Silveira C, A Nogara P, T da Rocha JB, F Faustino MA, D Rodrigues OE. Foletto P, et al. Among authors: dornelles l. Molecules. 2018 Oct 10;23(10):2588. doi: 10.3390/molecules23102588. Molecules. 2018. PMID: 30308960 Free PMC article.
Antiviral Effect of 5'-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection.
Tucci AR, da Rosa RM, Rosa AS, Augusto Chaves O, Ferreira VNS, Oliveira TKF, Coutinho Souza DD, Borba NRR, Dornelles L, Rocha NS, Mayer JCP, da Rocha JBT, Rodrigues OED, Miranda MD. Tucci AR, et al. Among authors: dornelles l. Molecules. 2023 Sep 19;28(18):6696. doi: 10.3390/molecules28186696. Molecules. 2023. PMID: 37764472 Free PMC article.
Synthesis and biological evaluation of new antioxidant and antiproliferative chalcogenobiotin derivatives for bladder carcinoma treatment.
Leitemberger A, Sonego MS, Garcia FD, Dos Santos ACF, Piccoli BC, da Silva FD, Oliveira CS, Seixas FK, Dornelles L, Rocha JBT, Nogara PA, Schachtschneider KM, Collares T, Rodrigues OED. Leitemberger A, et al. Among authors: dornelles l. Bioorg Med Chem. 2020 May 1;28(9):115423. doi: 10.1016/j.bmc.2020.115423. Epub 2020 Mar 16. Bioorg Med Chem. 2020. PMID: 32205047
Chalcogenium-AZT Derivatives: A Plausible Strategy To Tackle The RT-Inhibitors-Related Oxidative Stress While Maintaining Their Anti- HIV Properties.
Sarturi JM, Dornelles L, Segatto NV, Collares T, Seixas FK, Piccoli BC, da Silva FD, Omage FB, da Rocha JBT, Balaguez RA, Alves D, Lenardão EJ, Lopes EF, Kula-Pacurar A, Pyrc K, Sancineto L, Rodrigues OED. Sarturi JM, et al. Among authors: dornelles l. Curr Med Chem. 2023;30(21):2449-2462. doi: 10.2174/0929867329666220906095438. Curr Med Chem. 2023. PMID: 36065927
Evaluation of in vitro antioxidant effect of new mono and diselenides.
Stefanello ST, Prestes AS, Ogunmoyole T, Salman SM, Schwab RS, Brender CR, Dornelles L, Rocha JB, Soares FA. Stefanello ST, et al. Among authors: dornelles l. Toxicol In Vitro. 2013 Aug;27(5):1433-9. doi: 10.1016/j.tiv.2013.03.001. Epub 2013 Mar 14. Toxicol In Vitro. 2013. PMID: 23499633 Free article.
The insertion of functional groups in organic selenium compounds promote changes in mitochondrial parameters and raise the antibacterial activity.
Stefanello ST, Mizdal CR, Gonçalves DF, Hartmann DD, Dobrachinski F, de Carvalho NR, Salman SM, Sauer AC, Dornelles L, de Campos MMA, Soares FAA. Stefanello ST, et al. Among authors: dornelles l. Bioorg Chem. 2020 May;98:103727. doi: 10.1016/j.bioorg.2020.103727. Epub 2020 Mar 5. Bioorg Chem. 2020. PMID: 32179285
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