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The transmission interface of the Saccharomyces cerevisiae multidrug transporter Pdr5: Val-656 located in intracellular loop 2 plays a major role in drug resistance.
Downes MT, Mehla J, Ananthaswamy N, Wakschlag A, Lamonde M, Dine E, Ambudkar SV, Golin J. Downes MT, et al. Among authors: dine e. Antimicrob Agents Chemother. 2013 Feb;57(2):1025-34. doi: 10.1128/AAC.02133-12. Epub 2012 Dec 17. Antimicrob Agents Chemother. 2013. PMID: 23254431 Free PMC article.
A Genetic Incompatibility Accelerates Adaptation in Yeast.
Bui DT, Dine E, Anderson JB, Aquadro CF, Alani EE. Bui DT, et al. Among authors: dine e. PLoS Genet. 2015 Jul 31;11(7):e1005407. doi: 10.1371/journal.pgen.1005407. eCollection 2015 Jul. PLoS Genet. 2015. PMID: 26230253 Free PMC article.
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