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Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N. Sun H, et al. Among authors: deng t. Protein Cell. 2024 Feb 1;15(2):121-134. doi: 10.1093/procel/pwad040. Protein Cell. 2024. PMID: 37470320 Free PMC article.
SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates.
Li T, Zheng Q, Yu H, Wu D, Xue W, Xiong H, Huang X, Nie M, Yue M, Rong R, Zhang S, Zhang Y, Wu Y, Wang S, Zha Z, Chen T, Deng T, Wang Y, Zhang T, Chen Y, Yuan Q, Zhao Q, Zhang J, Gu Y, Li S, Xia N. Li T, et al. Among authors: deng t. Emerg Microbes Infect. 2020 Dec;9(1):2076-2090. doi: 10.1080/22221751.2020.1821583. Emerg Microbes Infect. 2020. PMID: 32897177 Free PMC article.
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Li T, Xue W, Zheng Q, Song S, Yang C, Xiong H, Zhang S, Hong M, Zhang Y, Yu H, Zhang Y, Sun H, Huang Y, Deng T, Chi X, Li J, Wang S, Zhou L, Chen T, Wang Y, Cheng T, Zhang T, Yuan Q, Zhao Q, Zhang J, McLellan JS, Zhou ZH, Zhang Z, Li S, Gu Y, Xia N. Li T, et al. Among authors: deng t. Nat Commun. 2021 Sep 27;12(1):5652. doi: 10.1038/s41467-021-25997-3. Nat Commun. 2021. PMID: 34580306 Free PMC article.
Characterization and immunogenicity of SARS-CoV-2 spike proteins with varied glycosylation.
Deng T, Li T, Chen G, Zhu Y, Xu L, Lin Y, Sun H, Zhang H, Fang Q, Hong J, Wu D, Gao S, Li S, Wang Y, Zhang T, Chen Y, Yuan Q, Zheng Q, Yu H, Zhao Q, Zhang J, Li S, Xia N, Gu Y. Deng T, et al. Vaccine. 2022 Nov 8;40(47):6839-6848. doi: 10.1016/j.vaccine.2022.09.057. Epub 2022 Sep 26. Vaccine. 2022. PMID: 36253220 Free PMC article.
1,893 results