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ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.
Arabzade A, Zhao Y, Varadharajan S, Chen HC, Jessa S, Rivas B, Stuckert AJ, Solis M, Kardian A, Tlais D, Golbourn BJ, Stanton AJ, Chan YS, Olson C, Karlin KL, Kong K, Kupp R, Hu B, Injac SG, Ngo M, Wang PR, De León LA, Sahm F, Kawauchi D, Pfister SM, Lin CY, Hodges HC, Singh I, Westbrook TF, Chintagumpala MM, Blaney SM, Parsons DW, Pajtler KW, Agnihotri S, Gilbertson RJ, Yi J, Jabado N, Kleinman CL, Bertrand KC, Deneen B, Mack SC. Arabzade A, et al. Among authors: deneen b. Cancer Discov. 2021 Sep;11(9):2200-2215. doi: 10.1158/2159-8290.CD-20-1066. Epub 2021 Mar 19. Cancer Discov. 2021. PMID: 33741710 Free PMC article.
PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis.
Yu K, Lin CJ, Hatcher A, Lozzi B, Kong K, Huang-Hobbs E, Cheng YT, Beechar VB, Zhu W, Zhang Y, Chen F, Mills GB, Mohila CA, Creighton CJ, Noebels JL, Scott KL, Deneen B. Yu K, et al. Among authors: deneen b. Nature. 2020 Feb;578(7793):166-171. doi: 10.1038/s41586-020-1952-2. Epub 2020 Jan 29. Nature. 2020. PMID: 31996845 Free PMC article.
ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors.
Kupp R, Ruff L, Terranova S, Nathan E, Ballereau S, Stark R, Sekhar Reddy Chilamakuri C, Hoffmann N, Wickham-Rahrmann K, Widdess M, Arabzade A, Zhao Y, Varadharajan S, Zheng T, Murugesan M, Pfister SM, Kawauchi D, Pajtler KW, Deneen B, Mack SC, Masih KE, Gryder BE, Khan J, Gilbertson RJ. Kupp R, et al. Among authors: deneen b. Cancer Discov. 2021 Sep;11(9):2216-2229. doi: 10.1158/2159-8290.CD-20-1052. Epub 2021 Mar 19. Cancer Discov. 2021. PMID: 33741711 Free PMC article.
POT1 Regulates Proliferation and Confers Sexual Dimorphism in Glioma.
Jalali A, Yu K, Beechar V, Bosquez Huerta NA, Grichuk A, Mehra D, Lozzi B, Kong K, Scott KL, Rao G, Bainbridge MN, Bondy ML, Deneen B. Jalali A, et al. Among authors: deneen b. Cancer Res. 2021 May 15;81(10):2703-2713. doi: 10.1158/0008-5472.CAN-20-3755. Epub 2021 Mar 29. Cancer Res. 2021. PMID: 33782098 Free PMC article.
Sox9 directs divergent epigenomic states in brain tumor subtypes.
Sardar D, Chen HC, Reyes A, Varadharajan S, Jain A, Mohila C, Curry R, Lozzi B, Rajendran K, Cervantes A, Yu K, Jalali A, Rao G, Mack SC, Deneen B. Sardar D, et al. Among authors: deneen b. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2202015119. doi: 10.1073/pnas.2202015119. Epub 2022 Jul 15. Proc Natl Acad Sci U S A. 2022. PMID: 35858326 Free PMC article.
Inhibitory input directs astrocyte morphogenesis through glial GABA B R.
Cheng YT, Luna-Figueroa E, Woo J, Chen HC, Lee ZF, Harmanci AS, Deneen B. Cheng YT, et al. Among authors: deneen b. bioRxiv [Preprint]. 2023 Mar 15:2023.03.14.532493. doi: 10.1101/2023.03.14.532493. bioRxiv. 2023. PMID: 36993256 Free PMC article. Updated. Preprint.
Inhibitory input directs astrocyte morphogenesis through glial GABABR.
Cheng YT, Luna-Figueroa E, Woo J, Chen HC, Lee ZF, Harmanci AS, Deneen B. Cheng YT, et al. Among authors: deneen b. Nature. 2023 May;617(7960):369-376. doi: 10.1038/s41586-023-06010-x. Epub 2023 Apr 26. Nature. 2023. PMID: 37100909 Free PMC article.
Next Directions in the Neuroscience of Cancers Arising outside the CNS.
Amit M, Anastasaki C, Dantzer R, Demir IE, Deneen B, Dixon KO, Egeblad M, Gibson EM, Hervey-Jumper SL, Hondermarck H, Magnon C, Monje M, Na'ara S, Pan Y, Repasky EA, Scheff NN, Sloan EK, Talbot S, Tracey KJ, Trotman LC, Valiente M, Van Aelst L, Venkataramani V, Venkatesh HS, Vermeer PD, Winkler F, Wong RJ, Gutmann DH, Borniger JC. Amit M, et al. Among authors: deneen b. Cancer Discov. 2024 Apr 4;14(4):669-673. doi: 10.1158/2159-8290.CD-23-1495. Cancer Discov. 2024. PMID: 38571430
92 results