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Codependencies of mTORC1 signaling and endolysosomal actin structures.
Priya A, Antoine-Bally S, Macé AS, Monteiro P, Sabatet V, Remy D, Dingli F, Loew D, Demetriades C, Gautreau AM, Chavrier P. Priya A, et al. Among authors: demetriades c. Sci Adv. 2023 Sep 15;9(37):eadd9084. doi: 10.1126/sciadv.add9084. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703363 Free PMC article.
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor.
Nicastro R, Brohée L, Alba J, Nüchel J, Figlia G, Kipschull S, Gollwitzer P, Romero-Pozuelo J, Fernandes SA, Lamprakis A, Vanni S, Teleman AA, De Virgilio C, Demetriades C. Nicastro R, et al. Among authors: demetriades c. Nat Cell Biol. 2023 Sep;25(9):1303-1318. doi: 10.1038/s41556-023-01198-6. Epub 2023 Aug 10. Nat Cell Biol. 2023. PMID: 37563253 Free PMC article.
mTORC1 activity negatively regulates human hair follicle growth and pigmentation.
Suzuki T, Chéret J, Scala FD, Akhundlu A, Gherardini J, Demetrius DL, O'Sullivan JDB, Kuka Epstein G, Bauman AJ, Demetriades C, Paus R. Suzuki T, et al. Among authors: demetriades c. EMBO Rep. 2023 Jul 5;24(7):e56574. doi: 10.15252/embr.202256574. Epub 2023 May 22. EMBO Rep. 2023. PMID: 37212043 Free PMC article.
A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids.
Gollwitzer P, Grützmacher N, Wilhelm S, Kümmel D, Demetriades C. Gollwitzer P, et al. Among authors: demetriades c. Nat Cell Biol. 2022 Sep;24(9):1394-1406. doi: 10.1038/s41556-022-00976-y. Epub 2022 Sep 12. Nat Cell Biol. 2022. PMID: 36097072 Free PMC article.
Schizoaffective Disorder and Concurrent Rhabdomyolysis.
Varkey T, Demetriades C, Malluru N, Merhavy ZI, Simtion K, Garmer C, Zeitler C, Pyada R, Nguyen AM, Ding JB. Varkey T, et al. Among authors: demetriades c. Cureus. 2021 Nov 25;13(11):e19896. doi: 10.7759/cureus.19896. eCollection 2021 Nov. Cureus. 2021. PMID: 34976507 Free PMC article.
35 results