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Lipotoxicity in human pancreatic islets and the protective effect of metformin.
Lupi R, Del Guerra S, Fierabracci V, Marselli L, Novelli M, Patanè G, Boggi U, Mosca F, Piro S, Del Prato S, Marchetti P. Lupi R, et al. Among authors: del guerra s, del prato s. Diabetes. 2002 Feb;51 Suppl 1:S134-7. doi: 10.2337/diabetes.51.2007.s134. Diabetes. 2002. PMID: 11815472
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.
Lupi R, Dotta F, Marselli L, Del Guerra S, Masini M, Santangelo C, Patané G, Boggi U, Piro S, Anello M, Bergamini E, Mosca F, Di Mario U, Del Prato S, Marchetti P. Lupi R, et al. Among authors: del guerra s, del prato s. Diabetes. 2002 May;51(5):1437-42. doi: 10.2337/diabetes.51.5.1437. Diabetes. 2002. PMID: 11978640
547 results