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New insights in Au-NHCs complexes as anticancer agents.
Porchia M, Pellei M, Marinelli M, Tisato F, Del Bello F, Santini C. Porchia M, et al. Among authors: del bello f. Eur J Med Chem. 2018 Feb 25;146:709-746. doi: 10.1016/j.ejmech.2018.01.065. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407992 Review.
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9. From 1,4-benzodioxane to 1,4-dioxane ring as a promising template of novel alpha1D-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents.
Quaglia W, Piergentili A, Del Bello F, Farande Y, Giannella M, Pigini M, Rafaiani G, Carrieri A, Amantini C, Lucciarini R, Santoni G, Poggesi E, Leonardi A. Quaglia W, et al. Among authors: del bello f. J Med Chem. 2008 Oct 23;51(20):6359-70. doi: 10.1021/jm800461k. Epub 2008 Sep 26. J Med Chem. 2008. PMID: 18817363
Structure-activity relationships in 1,4-benzodioxan-related compounds. 11. (1) reversed enantioselectivity of 1,4-dioxane derivatives in α1-adrenergic and 5-HT1A receptor binding sites recognition.
Bonifazi A, Piergentili A, Del Bello F, Farande Y, Giannella M, Pigini M, Amantini C, Nabissi M, Farfariello V, Santoni G, Poggesi E, Leonardi A, Menegon S, Quaglia W. Bonifazi A, et al. Among authors: del bello f. J Med Chem. 2013 Jan 24;56(2):584-8. doi: 10.1021/jm301525w. Epub 2013 Jan 8. J Med Chem. 2013. PMID: 23252794
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring.
Bonifazi A, Del Bello F, Mammoli V, Piergentili A, Petrelli R, Cimarelli C, Pellei M, Schepmann D, Wünsch B, Barocelli E, Bertoni S, Flammini L, Amantini C, Nabissi M, Santoni G, Vistoli G, Quaglia W. Bonifazi A, et al. Among authors: del bello f. J Med Chem. 2015 Nov 12;58(21):8601-15. doi: 10.1021/acs.jmedchem.5b01214. Epub 2015 Oct 14. J Med Chem. 2015. PMID: 26430967
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes.
Del Bello F, Bonifazi A, Giannella M, Giorgioni G, Piergentili A, Petrelli R, Cifani C, Micioni Di Bonaventura MV, Keck TM, Mazzolari A, Vistoli G, Cilia A, Poggesi E, Matucci R, Quaglia W. Del Bello F, et al. Eur J Med Chem. 2017 Jan 5;125:233-244. doi: 10.1016/j.ejmech.2016.09.026. Epub 2016 Sep 9. Eur J Med Chem. 2017. PMID: 27662034
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor.
Del Bello F, Cilia A, Carrieri A, Fasano DC, Ghelardini C, Di Cesare Mannelli L, Micheli L, Santini C, Diamanti E, Giannella M, Giorgioni G, Mammoli V, Paoletti CD, Petrelli R, Piergentili A, Quaglia W, Pigini M. Del Bello F, et al. ChemMedChem. 2016 Oct 19;11(20):2287-2298. doi: 10.1002/cmdc.201600383. Epub 2016 Sep 30. ChemMedChem. 2016. PMID: 27690321
Exploring the Role of N6-Substituents in Potent Dual Acting 5'-C-Ethyltetrazolyladenosine Derivatives: Synthesis, Binding, Functional Assays, and Antinociceptive Effects in Mice ∇.
Petrelli R, Scortichini M, Kachler S, Boccella S, Cerchia C, Torquati I, Del Bello F, Salvemini D, Novellino E, Luongo L, Maione S, Jacobson KA, Lavecchia A, Klotz KN, Cappellacci L. Petrelli R, et al. Among authors: del bello f. J Med Chem. 2017 May 25;60(10):4327-4341. doi: 10.1021/acs.jmedchem.7b00291. Epub 2017 May 5. J Med Chem. 2017. PMID: 28447789 Free PMC article.
69 results