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The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells.
Sabater L, Nicolau-Travers ML, De Rache A, Prado E, Dejeu J, Bombarde O, Lacroix J, Calsou P, Defrancq E, Mergny JL, Gomez D, Pratviel G. Sabater L, et al. Among authors: dejeu j. J Biol Inorg Chem. 2015 Jun;20(4):729-38. doi: 10.1007/s00775-015-1260-8. Epub 2015 Apr 7. J Biol Inorg Chem. 2015. PMID: 25846142
Cobalt(III)porphyrin to target G-quadruplex DNA.
Sabater L, Fang PJ, Chang CF, De Rache A, Prado E, Dejeu J, Garofalo A, Lin JH, Mergny JL, Defrancq E, Pratviel G. Sabater L, et al. Among authors: dejeu j. Dalton Trans. 2015 Feb 28;44(8):3701-7. doi: 10.1039/c4dt03631j. Dalton Trans. 2015. PMID: 25573281
Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties.
Flack T, Constantin T, Penasse S, Dejeu J, Gennaro B, Jourdan M, Laguerre A, Pirrotta M, Monchaud D, Spinelli N, Defrancq E. Flack T, et al. Among authors: dejeu j. Chemistry. 2016 Jan 26;22(5):1760-7. doi: 10.1002/chem.201504572. Epub 2015 Dec 21. Chemistry. 2016. PMID: 26689623
Efficient Inhibition of Telomerase by Nickel-Salophen Complexes.
Lecarme L, Prado E, De Rache A, Nicolau-Travers ML, Gellon G, Dejeu J, Lavergne T, Jamet H, Gomez D, Mergny JL, Defrancq E, Jarjayes O, Thomas F. Lecarme L, et al. Among authors: dejeu j. ChemMedChem. 2016 Jun 6;11(11):1133-6. doi: 10.1002/cmdc.201600171. Epub 2016 May 11. ChemMedChem. 2016. PMID: 27166712
New Ruthenium-Based Probes for Selective G-Quadruplex Targeting.
Piraux G, Bar L, Abraham M, Lavergne T, Jamet H, Dejeu J, Marcélis L, Defrancq E, Elias B. Piraux G, et al. Among authors: dejeu j. Chemistry. 2017 Sep 4;23(49):11872-11880. doi: 10.1002/chem.201702076. Epub 2017 Aug 7. Chemistry. 2017. PMID: 28609545
40 results