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The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma.
Chang C, Rajasekaran M, Qiao Y, Dong H, Wang Y, Xia H, Deivasigamani A, Wu M, Sekar K, Gao H, Sun M, Niu Y, Li Q, Tao L, Yan Z, Wang M, Chen S, Zhao S, Chen D, Li L, Yang F, Gao H, Chen B, Su L, Xu L, Chen Y, Seshachalam VP, Chen G, Gunaratne J, Hong W, Shi J, Chen G, Grierson DS, Chabot B, Xie T, Hui KM, Chen J. Chang C, et al. Among authors: deivasigamani a. Nat Commun. 2022 Mar 16;13(1):1363. doi: 10.1038/s41467-022-29016-x. Nat Commun. 2022. PMID: 35296659 Free PMC article.
Genome-wide CRISPR knockout screens identify NCAPG as an essential oncogene for hepatocellular carcinoma tumor growth.
Wang Y, Gao B, Tan PY, Handoko YA, Sekar K, Deivasigamani A, Seshachalam VP, OuYang HY, Shi M, Xie C, Goh BKP, Ooi LL, Man Hui K. Wang Y, et al. Among authors: deivasigamani a. FASEB J. 2019 Aug;33(8):8759-8770. doi: 10.1096/fj.201802213RR. Epub 2019 Apr 25. FASEB J. 2019. PMID: 31022357 Free PMC article.
In conclusion, NCAPG is an essential gene for HCC tumor cell survival. It represents a promising novel target for treating HCC and a prognostic biomarker for clinical management of HCC.-Wang, Y., Gao, B., Tan, P. Y., Handoko, Y. A., Sekar, K., Deivasigaman …
In conclusion, NCAPG is an essential gene for HCC tumor cell survival. It represents a promising novel target for treating HCC and …
Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma.
Lee JH, Mohan CD, Deivasigamani A, Jung YY, Rangappa S, Basappa S, Chinnathambi A, Alahmadi TA, Alharbi SA, Garg M, Lin ZX, Rangappa KS, Sethi G, Hui KM, Ahn KS. Lee JH, et al. Among authors: deivasigamani a. J Adv Res. 2020 Jul 13;26:83-94. doi: 10.1016/j.jare.2020.07.004. eCollection 2020 Nov. J Adv Res. 2020. PMID: 33133685 Free PMC article.
Correlation of NUF2 Overexpression with Poorer Patient Survival in Multiple Cancers.
Jiang X, Jiang Y, Luo S, Sekar K, Koh CKT, Deivasigamani A, Dong Q, Zhang N, Li S, Hao F, Goh BKP, Ooi LL, Wang Y, Hui KM. Jiang X, et al. Among authors: deivasigamani a. Cancer Res Treat. 2021 Oct;53(4):944-961. doi: 10.4143/crt.2020.466. Epub 2020 Jan 4. Cancer Res Treat. 2021. PMID: 33421974 Free PMC article.
27 results