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Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites.
Jarrad AM, Karoli T, Debnath A, Tay CY, Huang JX, Kaeslin G, Elliott AG, Miyamoto Y, Ramu S, Kavanagh AM, Zuegg J, Eckmann L, Blaskovich MA, Cooper MA. Jarrad AM, et al. Among authors: debnath a. Eur J Med Chem. 2015 Aug 28;101:96-102. doi: 10.1016/j.ejmech.2015.06.019. Epub 2015 Jun 18. Eur J Med Chem. 2015. PMID: 26117821 Free PMC article.
Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.
Debnath A, Shahinas D, Bryant C, Hirata K, Miyamoto Y, Hwang G, Gut J, Renslo AR, Pillai DR, Eckmann L, Reed SL, McKerrow JH. Debnath A, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):4138-44. doi: 10.1128/AAC.02576-14. Epub 2014 May 12. Antimicrob Agents Chemother. 2014. PMID: 24820073 Free PMC article.
Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo.
Hopper M, Yun JF, Zhou B, Le C, Kehoe K, Le R, Hill R, Jongeward G, Debnath A, Zhang L, Miyamoto Y, Eckmann L, Land KM, Wrischnik LA. Hopper M, et al. Among authors: debnath a. Int J Antimicrob Agents. 2016 Dec;48(6):690-694. doi: 10.1016/j.ijantimicag.2016.09.020. Epub 2016 Nov 2. Int J Antimicrob Agents. 2016. PMID: 27839893 Free PMC article.
Susceptibility Testing of Medically Important Parasites.
Genetu Bayih A, Debnath A, Mitre E, Huston CD, Laleu B, Leroy D, Blasco B, Campo B, Wells TNC, Willis PA, Sjö P, Van Voorhis WC, Pillai DR. Genetu Bayih A, et al. Among authors: debnath a. Clin Microbiol Rev. 2017 Jul;30(3):647-669. doi: 10.1128/CMR.00111-16. Clin Microbiol Rev. 2017. PMID: 28446445 Free PMC article. Review.
Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity.
Jarrad AM, Ang CW, Debnath A, Hahn HJ, Woods K, Tan L, Sykes ML, Jones AJ, Pelingon R, Butler MS, Avery VM, West NP, Karoli T, Blaskovich MAT, Cooper MA. Jarrad AM, et al. Among authors: debnath a. J Med Chem. 2018 Dec 27;61(24):11349-11371. doi: 10.1021/acs.jmedchem.8b01578. Epub 2018 Dec 11. J Med Chem. 2018. PMID: 30468386 Free PMC article.
361 results