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MicroRNA-122 and cytokeratin-18 have potential as a biomarkers of drug-induced liver injury in European and African patients on treatment for mycobacterial infection.
Rupprechter SAE, Sloan DJ, Oosthuyzen W, Bachmann TT, Hill AT, Dhaliwal K, Templeton K, Matovu J, Sekaggya-Wiltshire C, Dear JW. Rupprechter SAE, et al. Among authors: dear jw. Br J Clin Pharmacol. 2021 Aug;87(8):3206-3217. doi: 10.1111/bcp.14736. Epub 2021 Jan 26. Br J Clin Pharmacol. 2021. PMID: 33432705 Free PMC article.
Microfluidic system for near-patient extraction and detection of miR-122 microRNA biomarker for drug-induced liver injury diagnostics.
Kersaudy-Kerhoas M, Liga A, Roychoudhury A, Stamouli M, Grant R, Carrera DS, Schulze H, Mielczarek W, Oosthuyzen W, Quintana JF, Dickinson P, Buck AH, Leslie NR, Haas J, Bachmann TT, Dear JW. Kersaudy-Kerhoas M, et al. Among authors: dear jw. Biomicrofluidics. 2022 Apr 18;16(2):024108. doi: 10.1063/5.0085078. eCollection 2022 Mar. Biomicrofluidics. 2022. PMID: 35464137 Free PMC article.
miR-122 direct detection in human serum by time-gated fluorescence imaging.
Garcia-Fernandez E, Gonzalez-Garcia MC, Pernagallo S, Ruedas-Rama MJ, Fara MA, López-Delgado FJ, Dear JW, Ilyine H, Ress C, Díaz-Mochón JJ, Orte A. Garcia-Fernandez E, et al. Among authors: dear jw. Chem Commun (Camb). 2019 Dec 25;55(99):14958-14961. doi: 10.1039/c9cc08069d. Epub 2019 Nov 27. Chem Commun (Camb). 2019. PMID: 31774422 Free article.
Direct Detection of miR-122 in Hepatotoxicity Using Dynamic Chemical Labeling Overcomes Stability and isomiR Challenges.
López-Longarela B, Morrison EE, Tranter JD, Chahman-Vos L, Léonard JF, Gautier JC, Laurent S, Lartigau A, Boitier E, Sautier L, Carmona-Saez P, Martorell-Marugan J, Mellanby RJ, Pernagallo S, Ilyine H, Rissin DM, Duffy DC, Dear JW, Díaz-Mochón JJ. López-Longarela B, et al. Among authors: dear jw. Anal Chem. 2020 Feb 18;92(4):3388-3395. doi: 10.1021/acs.analchem.9b05449. Epub 2020 Jan 27. Anal Chem. 2020. PMID: 31939284 Free article.
Systems analysis of miRNA biomarkers to inform drug safety.
Schofield AL, Brown JP, Brown J, Wilczynska A, Bell C, Glaab WE, Hackl M, Howell L, Lee S, Dear JW, Remes M, Reeves P, Zhang E, Allmer J, Norris A, Falciani F, Takeshita LY, Seyed Forootan S, Sutton R, Park BK, Goldring C. Schofield AL, et al. Among authors: dear jw. Arch Toxicol. 2021 Nov;95(11):3475-3495. doi: 10.1007/s00204-021-03150-9. Epub 2021 Sep 12. Arch Toxicol. 2021. PMID: 34510227 Free PMC article. Review.
168 results