Dang Q - Search Results

1

Design of prodrugs to enhance colonic absorption by increasing lipophilicity and blocking ionization.

Nofsinger R, Clas SD, Sanchez RI, Walji A, Manser K, Nissley B, Balsells J, Nair A, Dang Q, Bennett DJ, Hafey M, Wang J, Higgins J, Templeton A, Coleman P, Grobler J, Smith R, Wu Y. Nofsinger R, et al. Among authors: dang q. Pharmaceuticals (Basel). 2014 Feb 24;7(2):207-19. doi: 10.3390/ph7020207. Pharmaceuticals (Basel). 2014. PMID: 24566521 Free PMC article.

2

Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.

Walji AM, Sanchez RI, Clas SD, Nofsinger R, de Lera Ruiz M, Li J, Bennet A, John C, Bennett DJ, Sanders JM, Di Marco CN, Kim SH, Balsells J, Ceglia SS, Dang Q, Manser K, Nissley B, Wai JS, Hafey M, Wang J, Chessen G, Templeton A, Higgins J, Smith R, Wu Y, Grobler J, Coleman PJ. Walji AM, et al. Among authors: dang q. ChemMedChem. 2015 Feb;10(2):245-52. doi: 10.1002/cmdc.201402393. Epub 2014 Dec 2. ChemMedChem. 2015. PMID: 25469982

3

Aromatic dienophiles. 1. A theoretical study of an inverse-electron demand Diels-Alder reaction between 2-aminopyrrole and 1,3,5-triazine.

Yu ZX, Dang Q, Wu YD. Yu ZX, et al. Among authors: dang q. J Org Chem. 2001 Sep 7;66(18):6029-36. doi: 10.1021/jo010243p. J Org Chem. 2001. PMID: 11529728

4

Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase.

Dang Q, Liu Y, Cashion DK, Kasibhatla SR, Jiang T, Taplin F, Jacintho JD, Li H, Sun Z, Fan Y, DaRe J, Tian F, Li W, Gibson T, Lemus R, van Poelje PD, Potter SC, Erion MD. Dang Q, et al. J Med Chem. 2011 Jan 13;54(1):153-65. doi: 10.1021/jm101035x. Epub 2010 Dec 2. J Med Chem. 2011. PMID: 21126019

5

Clarification of the mechanism of the cascade reactions between amino-substituted heterocycles and 1,3,5-triazines.

Yu ZX, Dang Q, Wu YD. Yu ZX, et al. Among authors: dang q. J Org Chem. 2005 Feb 4;70(3):998-1005. doi: 10.1021/jo049248n. J Org Chem. 2005. PMID: 15675860

6

Reaction of Aldehydes/Ketones with Electron-Deficient 1,3,5-Triazines Leading to Functionalized Pyrimidines as Diels-Alder/Retro-Diels-Alder Reaction Products: Reaction Development and Mechanistic Studies.

Yang K, Dang Q, Cai PJ, Gao Y, Yu ZX, Bai X. Yang K, et al. Among authors: dang q. J Org Chem. 2017 Mar 3;82(5):2336-2344. doi: 10.1021/acs.joc.6b02570. Epub 2017 Feb 10. J Org Chem. 2017. PMID: 28112917

7

Synthesis of hexahydrobenzo[b]pyrimido[4,5-h][1,6]naphthyridines via an intramolecular hetero-Diels-Alder reaction.

Yang F, Zheng L, Xiang J, Dang Q, Bai X. Yang F, et al. Among authors: dang q. J Comb Chem. 2010 Jul 12;12(4):476-81. doi: 10.1021/cc100018b. J Comb Chem. 2010. PMID: 20550172

8

Aromatic Heterocycles as Productive Dienophiles in the Inverse Electron-Demand Diels-Alder Reactions of 1,3,5-Triazines.

Xu G, Bai X, Dang Q. Xu G, et al. Among authors: dang q. Acc Chem Res. 2020 Apr 21;53(4):773-781. doi: 10.1021/acs.accounts.9b00604. Epub 2020 Mar 31. Acc Chem Res. 2020. PMID: 32227911

9

Stereochemistry as a tool in deciphering the processes of a tandem iminium cyclization and Smiles rearrangement.

Xiang J, Zhu T, Dang Q, Bai X. Xiang J, et al. Among authors: dang q. J Org Chem. 2010 Dec 3;75(23):8147-54. doi: 10.1021/jo101798p. Epub 2010 Nov 9. J Org Chem. 2010. PMID: 21062053

10

Synthesis of novel pyrimidine fused 8-membered heterocycles via iminium ion cyclization reactions.

Che X, Zheng L, Dang Q, Bai X. Che X, et al. Among authors: dang q. J Org Chem. 2008 Feb 1;73(3):1147-9. doi: 10.1021/jo7020746. Epub 2008 Jan 8. J Org Chem. 2008. PMID: 18179230

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