D'Argenio DZ - Search Results

1

Plasma pharmacokinetics, oral bioavailability, and interspecies scaling of the DNA methyltransferase inhibitor, zebularine.

Holleran JL, Parise RA, Joseph E, Eiseman JL, Covey JM, Glaze ER, Lyubimov AV, Chen YF, D'Argenio DZ, Egorin MJ. Holleran JL, et al. Clin Cancer Res. 2005 May 15;11(10):3862-8. doi: 10.1158/1078-0432.CCR-04-2406. Clin Cancer Res. 2005. PMID: 15897587

2

A mass balance and disposition study of the DNA methyltransferase inhibitor zebularine (NSC 309132) and three of its metabolites in mice.

Beumer JH, Joseph E, Egorin MJ, Parker RS, D'argenio DZ, Covey JM, Eiseman JL. Beumer JH, et al. Clin Cancer Res. 2006 Oct 1;12(19):5826-33. doi: 10.1158/1078-0432.CCR-06-1234. Clin Cancer Res. 2006. PMID: 17020990

3

Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice.

Beumer JH, Eiseman JL, Parise RA, Florian JA Jr, Joseph E, D'Argenio DZ, Parker RS, Kay B, Covey JM, Egorin MJ. Beumer JH, et al. Cancer Chemother Pharmacol. 2008 Aug;62(3):457-64. doi: 10.1007/s00280-007-0625-2. Epub 2007 Nov 15. Cancer Chemother Pharmacol. 2008. PMID: 18008070 Free PMC article.

4

Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice.

Beumer JH, Eiseman JL, Gilbert JA, Holleran JL, Yellow-Duke AE, Clausen DM, D'Argenio DZ, Ames MM, Hershberger PA, Parise RA, Bai L, Covey JM, Egorin MJ. Beumer JH, et al. Cancer Chemother Pharmacol. 2011 Feb;67(2):421-30. doi: 10.1007/s00280-010-1337-6. Epub 2010 May 5. Cancer Chemother Pharmacol. 2011. PMID: 20443002 Free PMC article.

5

Pharmacodynamic model of topotecan-induced time course of neutropenia.

Zamboni WC, D'Argenio DZ, Stewart CF, MacVittie T, Delauter BJ, Farese AM, Potter DM, Kubat NM, Tubergen D, Egorin MJ. Zamboni WC, et al. Clin Cancer Res. 2001 Aug;7(8):2301-8. Clin Cancer Res. 2001. PMID: 11489805

6

A local effect of CYP24 inhibition on lung tumor xenograft exposure to 1,25-dihydroxyvitamin D(3) is revealed using a novel LC-MS/MS assay.

Beumer JH, Parise RA, Kanterewicz B, Petkovich M, D'Argenio DZ, Hershberger PA. Beumer JH, et al. Steroids. 2012 Apr;77(5):477-83. doi: 10.1016/j.steroids.2012.01.007. Epub 2012 Jan 20. Steroids. 2012. PMID: 22285938 Free PMC article.

7

Physiologically-based pharmacokinetics and molecular pharmacodynamics of 17-(allylamino)-17-demethoxygeldanamycin and its active metabolite in tumor-bearing mice.

Xu L, Eiseman JL, Egorin MJ, D'Argenio DZ. Xu L, et al. J Pharmacokinet Pharmacodyn. 2003 Jun;30(3):185-219. doi: 10.1023/a:1025542026488. J Pharmacokinet Pharmacodyn. 2003. PMID: 14571691

8

Pharmacokinetics of doxycycline in adults with cystic fibrosis.

Beringer PM, Owens H, Nguyen A, Benitez D, Rao A, D'Argenio DZ. Beringer PM, et al. Antimicrob Agents Chemother. 2012 Jan;56(1):70-4. doi: 10.1128/AAC.05710-11. Epub 2011 Oct 24. Antimicrob Agents Chemother. 2012. PMID: 22024822 Free PMC article. Clinical Trial.

9

RAD-ADAPT: Software for modelling clonogenic assay data in radiation biology.

Zhang Y, Hu K, Beumer JH, Bakkenist CJ, D'Argenio DZ. Zhang Y, et al. DNA Repair (Amst). 2017 Apr;52:24-30. doi: 10.1016/j.dnarep.2017.02.004. Epub 2017 Feb 20. DNA Repair (Amst). 2017. PMID: 28254357 Free PMC article.

10

Predicting monoclonal antibody pharmacokinetics following subcutaneous administration via whole-body physiologically-based modeling.

Hu S, D'Argenio DZ. Hu S, et al. J Pharmacokinet Pharmacodyn. 2020 Oct;47(5):385-409. doi: 10.1007/s10928-020-09691-3. Epub 2020 Jun 4. J Pharmacokinet Pharmacodyn. 2020. PMID: 32500362 Free PMC article.

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