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Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease.
Henderson MX, Covell DJ, Chung CH, Pitkin RM, Sandler RM, Decker SC, Riddle DM, Zhang B, Gathagan RJ, James MJ, Trojanowski JQ, Brunden KR, Lee VMY, Luk KC. Henderson MX, et al. Among authors: covell dj. Neurobiol Dis. 2020 Mar;136:104712. doi: 10.1016/j.nbd.2019.104712. Epub 2019 Dec 16. Neurobiol Dis. 2020. PMID: 31837422 Free PMC article.
Novel conformation-selective alpha-synuclein antibodies raised against different in vitro fibril forms show distinct patterns of Lewy pathology in Parkinson's disease.
Covell DJ, Robinson JL, Akhtar RS, Grossman M, Weintraub D, Bucklin HM, Pitkin RM, Riddle D, Yousef A, Trojanowski JQ, Lee VM. Covell DJ, et al. Neuropathol Appl Neurobiol. 2017 Dec;43(7):604-620. doi: 10.1111/nan.12402. Epub 2017 May 15. Neuropathol Appl Neurobiol. 2017. PMID: 28386933 Free PMC article.
Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein.
Tuttle MD, Comellas G, Nieuwkoop AJ, Covell DJ, Berthold DA, Kloepper KD, Courtney JM, Kim JK, Barclay AM, Kendall A, Wan W, Stubbs G, Schwieters CD, Lee VM, George JM, Rienstra CM. Tuttle MD, et al. Among authors: covell dj. Nat Struct Mol Biol. 2016 May;23(5):409-15. doi: 10.1038/nsmb.3194. Epub 2016 Mar 28. Nat Struct Mol Biol. 2016. PMID: 27018801 Free PMC article.
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