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Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of Kendine 91, a novel histone deacetylase inhibitor, in mice plasma and tissues: application to a pharmacokinetic study.
Otaegui D, Rodríguez-Gascón A, Zubia A, Cossío FP, Pedraz JL. Otaegui D, et al. Among authors: cossio fp. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jul 1;870(1):109-16. doi: 10.1016/j.jchromb.2008.06.013. Epub 2008 Jun 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2008. PMID: 18583203
Application of stereocontrolled stepwise [3+2] cycloadditions to the preparation of inhibitors of alpha4beta1-integrin-mediated hepatic melanoma metastasis.
Zubia A, Mendoza L, Vivanco S, Aldaba E, Carrascal T, Lecea B, Arrieta A, Zimmerman T, Vidal-Vanaclocha F, Cossio FP. Zubia A, et al. Among authors: cossio fp. Angew Chem Int Ed Engl. 2005 May 6;44(19):2903-7. doi: 10.1002/anie.200462497. Angew Chem Int Ed Engl. 2005. PMID: 15827972 No abstract available.
Synthesis of 11C-labeled Kendine 91, a histone deacetylase inhibitor.
Aginagalde M, Gómez-Vallejo V, Vara Y, Cossío FP, Llop J. Aginagalde M, et al. Among authors: cossio fp. Appl Radiat Isot. 2012 Oct;70(10):2552-7. doi: 10.1016/j.apradiso.2012.05.016. Epub 2012 Jun 7. Appl Radiat Isot. 2012. PMID: 22871301
Design, synthesis, and functional evaluation of leukocyte function associated antigen-1 antagonists in early and late stages of cancer development.
San Sebastián E, Zimmerman T, Zubia A, Vara Y, Martin E, Sirockin F, Dejaegere A, Stote RH, Lopez X, Pantoja-Uceda D, Valcárcel M, Mendoza L, Vidal-Vanaclocha F, Cossío FP, Blanco FJ. San Sebastián E, et al. Among authors: cossio fp. J Med Chem. 2013 Feb 14;56(3):735-47. doi: 10.1021/jm3016848. Epub 2013 Jan 22. J Med Chem. 2013. PMID: 23339734
Development and validation of a LC-MS assay for the quantification of ikh12 a novel anti-tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study.
Otaegui D, Masdeu C, Aldaba E, Vara Y, Zubia A, San Sebastian E, Alcalá M, Villafruela S, Cossío FP, Rodriguez-Gascón A. Otaegui D, et al. Among authors: cossio fp. Biomed Chromatogr. 2015 Aug;29(8):1249-58. doi: 10.1002/bmc.3414. Epub 2015 Jan 23. Biomed Chromatogr. 2015. PMID: 25616154
In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma.
Pérez-Salvia M, Aldaba E, Vara Y, Fabre M, Ferrer C, Masdeu C, Zubia A, Sebastian ES, Otaegui D, Llinàs-Arias P, Rosselló-Tortella M, Berdasco M, Moutinho C, Setien F, Villanueva A, González-Barca E, Muncunill J, Navarro JT, Piris MA, Cossio FP, Esteller M. Pérez-Salvia M, et al. Among authors: cossio fp. Haematologica. 2018 Nov;103(11):e537-e540. doi: 10.3324/haematol.2018.189241. Epub 2018 Jun 7. Haematologica. 2018. PMID: 29880608 Free PMC article. No abstract available.
Biodistribution and metabolism of 11C-labeled Kendine 91 in mice and rats.
Gómez-Vallejo V, Martín A, Aginagalde M, San Sebastian E, Padro D, Cossío FP, Llop J. Gómez-Vallejo V, et al. Among authors: cossio fp. Appl Radiat Isot. 2012 Oct;70(10):2545-51. doi: 10.1016/j.apradiso.2012.05.020. Epub 2012 Jun 9. Appl Radiat Isot. 2012. PMID: 22871302
184 results