In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma

Haematologica. 2018 Nov;103(11):e537-e540. doi: 10.3324/haematol.2018.189241. Epub 2018 Jun 7.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • A549 Cells
  • Animals
  • HCT116 Cells
  • Hep G2 Cells
  • Histone Deacetylase 6 / antagonists & inhibitors*
  • Histone Deacetylase 6 / genetics
  • Histone Deacetylase 6 / metabolism
  • Histone Deacetylase Inhibitors / chemical synthesis
  • Histone Deacetylase Inhibitors / chemistry
  • Histone Deacetylase Inhibitors / pharmacology*
  • Humans
  • Lymphoma, Mantle-Cell / drug therapy*
  • Lymphoma, Mantle-Cell / enzymology
  • Lymphoma, Mantle-Cell / genetics
  • Lymphoma, Mantle-Cell / metabolism
  • MCF-7 Cells
  • Mice
  • Mice, SCID
  • Neoplasm Proteins / antagonists & inhibitors*
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism
  • PC-3 Cells
  • Xenograft Model Antitumor Assays

Substances

  • Histone Deacetylase Inhibitors
  • Neoplasm Proteins
  • HDAC6 protein, human
  • Histone Deacetylase 6