Cook SJ - Search Results

1

Macroautophagy is repressed during mitosis - seeing is believing.

Odle RI, Cook SJ. Odle RI, et al. Among authors: cook sj. Autophagy. 2020 Apr;16(4):775-776. doi: 10.1080/15548627.2020.1725405. Epub 2020 Feb 20. Autophagy. 2020. PMID: 32079445 Free PMC article. Review.

2

An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis.

Odle RI, Walker SA, Oxley D, Kidger AM, Balmanno K, Gilley R, Okkenhaug H, Florey O, Ktistakis NT, Cook SJ. Odle RI, et al. Among authors: cook sj. Mol Cell. 2020 Jan 16;77(2):228-240.e7. doi: 10.1016/j.molcel.2019.10.016. Epub 2019 Nov 13. Mol Cell. 2020. PMID: 31733992 Free PMC article.

3

Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2.

Kidger AM, Munck JM, Saini HK, Balmanno K, Minihane E, Courtin A, Graham B, O'Reilly M, Odle R, Cook SJ. Kidger AM, et al. Among authors: cook sj. Mol Cancer Ther. 2020 Feb;19(2):525-539. doi: 10.1158/1535-7163.MCT-19-0505. Epub 2019 Nov 20. Mol Cancer Ther. 2020. PMID: 31748345

4

CDK1, the Other 'Master Regulator' of Autophagy.

Odle RI, Florey O, Ktistakis NT, Cook SJ. Odle RI, et al. Among authors: cook sj. Trends Cell Biol. 2021 Feb;31(2):95-107. doi: 10.1016/j.tcb.2020.11.001. Epub 2020 Nov 30. Trends Cell Biol. 2021. PMID: 33272830 Free article. Review.

5

Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.

Garner AP, Weston CR, Todd DE, Balmanno K, Cook SJ. Garner AP, et al. Among authors: cook sj. Oncogene. 2002 Nov 21;21(53):8089-104. doi: 10.1038/sj.onc.1206000. Oncogene. 2002. PMID: 12444545

6

Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.

Gillings AS, Balmanno K, Wiggins CM, Johnson M, Cook SJ. Gillings AS, et al. Among authors: cook sj. FEBS J. 2009 Nov;276(21):6050-62. doi: 10.1111/j.1742-4658.2009.07329.x. Epub 2009 Sep 29. FEBS J. 2009. PMID: 19788418 Free article. Review.

7

CDK1, not ERK1/2 or ERK5, is required for mitotic phosphorylation of BIMEL.

Gilley R, Lochhead PA, Balmanno K, Oxley D, Clark J, Cook SJ. Gilley R, et al. Among authors: cook sj. Cell Signal. 2012 Jan;24(1):170-80. doi: 10.1016/j.cellsig.2011.08.018. Epub 2011 Sep 8. Cell Signal. 2012. PMID: 21924351

8

ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway.

Kidger AM, Sipthorp J, Cook SJ. Kidger AM, et al. Among authors: cook sj. Pharmacol Ther. 2018 Jul;187:45-60. doi: 10.1016/j.pharmthera.2018.02.007. Epub 2018 Feb 16. Pharmacol Ther. 2018. PMID: 29454854 Review.

9

Inhibition of RAF dimers: it takes two to tango.

Cook FA, Cook SJ. Cook FA, et al. Among authors: cook sj. Biochem Soc Trans. 2021 Feb 26;49(1):237-251. doi: 10.1042/BST20200485. Biochem Soc Trans. 2021. PMID: 33367512 Free PMC article. Review.

10

Inhibitory feedback control of NF-κB signalling in health and disease.

Prescott JA, Mitchell JP, Cook SJ. Prescott JA, et al. Among authors: cook sj. Biochem J. 2021 Jul 16;478(13):2619-2664. doi: 10.1042/BCJ20210139. Biochem J. 2021. PMID: 34269817 Free PMC article. Review.

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