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An effective in vitro and in vivo antileishmanial activity and mechanism of action of 8-hydroxyquinoline against Leishmania species causing visceral and tegumentary leishmaniasis.
Costa Duarte M, dos Reis Lage LM, Lage DP, Mesquita JT, Salles BC, Lavorato SN, Menezes-Souza D, Roatt BM, Alves RJ, Tavares CA, Tempone AG, Coelho EA. Costa Duarte M, et al. Vet Parasitol. 2016 Feb 15;217:81-8. doi: 10.1016/j.vetpar.2016.01.002. Epub 2016 Jan 7. Vet Parasitol. 2016. PMID: 26827866
Antileishmanial activity of a naphthoquinone derivate against promastigote and amastigote stages of Leishmania infantum and Leishmania amazonensis and its mechanism of action against L. amazonensis species.
Mendonça DVC, Lage DP, Calixto SL, Ottoni FM, Tavares GSV, Ludolf F, Chávez-Fumagalli MA, Schneider MS, Duarte MC, Tavares CAP, Alves RJ, Coimbra ES, Coelho EAF. Mendonça DVC, et al. Among authors: coelho eaf. Parasitol Res. 2018 Feb;117(2):391-403. doi: 10.1007/s00436-017-5713-6. Epub 2017 Dec 16. Parasitol Res. 2018. PMID: 29248978
Antileishmanial Activity, Cytotoxicity and Mechanism of Action of Clioquinol Against Leishmania infantum and Leishmania amazonensis Species.
Tavares GSV, Mendonça DVC, Lage DP, Granato JDT, Ottoni FM, Ludolf F, Chávez-Fumagalli MA, Duarte MC, Tavares CAP, Alves RJ, Coimbra ES, Coelho EAF. Tavares GSV, et al. Among authors: coelho eaf. Basic Clin Pharmacol Toxicol. 2018 Sep;123(3):236-246. doi: 10.1111/bcpt.12990. Epub 2018 Apr 6. Basic Clin Pharmacol Toxicol. 2018. PMID: 29481714 Free article.
Parasitological and immunological evaluation of a quinoline derivative salt incorporated into a polymeric micelle formulation against Leishmania infantum infection.
Ribeiro Antinarelli LM, Glanzmann N, Mendonça DVC, Lage DP, Oliveira-da-Silva JA, Tavares GSV, Carvalho AMRS, Freitas CS, Martins VT, Duarte MC, Menezes-Souza D, da Silva AD, Coelho EAF, Soares Coimbra E. Ribeiro Antinarelli LM, et al. Among authors: coelho eaf. Parasitol Res. 2022 Jul;121(7):2129-2140. doi: 10.1007/s00436-022-07544-1. Epub 2022 May 26. Parasitol Res. 2022. PMID: 35614147 Free PMC article.
Exploring the repositioning of the amodiaquine as potential drug against visceral leishmaniasis: The in vitro effect against Leishmania infantum is associated with multiple mechanisms, involving mitochondria dysfunction, oxidative stress and loss of cell cycle control.
Antinarelli LMR, Midlej V, da Silva EDS, Coelho EAF, da Silva AD, Coimbra ES. Antinarelli LMR, et al. Among authors: coelho eaf. Chem Biol Interact. 2023 Feb 1;371:110333. doi: 10.1016/j.cbi.2022.110333. Epub 2022 Dec 30. Chem Biol Interact. 2023. PMID: 36592711
Synthesis of 1,2,3-Triazole-Containing Methoxylated Cinnamides and Their Antileishmanial Activity against the Leishmania braziliensis Species.
Santos FSD, Freitas RP, Freitas CS, Mendonça DVC, Lage DP, Tavares GSV, Machado AS, Martins VT, Costa AV, Queiroz VT, de Oliveira MB, Oliveira FM, Antinarelli LMR, Coimbra ES, Pilau EJ, da Silva GP, Coelho EAF, Teixeira RR. Santos FSD, et al. Among authors: coelho eaf. Pharmaceuticals (Basel). 2023 Aug 7;16(8):1113. doi: 10.3390/ph16081113. Pharmaceuticals (Basel). 2023. PMID: 37631028 Free PMC article.
Immune responses induced by the Leishmania (Leishmania) donovani A2 antigen, but not by the LACK antigen, are protective against experimental Leishmania (Leishmania) amazonensis infection.
Coelho EA, Tavares CA, Carvalho FA, Chaves KF, Teixeira KN, Rodrigues RC, Charest H, Matlashewski G, Gazzinelli RT, Fernandes AP. Coelho EA, et al. Infect Immun. 2003 Jul;71(7):3988-94. doi: 10.1128/IAI.71.7.3988-3994.2003. Infect Immun. 2003. PMID: 12819086 Free PMC article.
173 results