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Lifelong voluntary aerobic exercise prevents age- and Western diet- induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice.
Gioscia-Ryan RA, Clayton ZS, Zigler MC, Richey JJ, Cuevas LM, Rossman MJ, Battson ML, Ziemba BP, Hutton DA, VanDongen NS, Seals DR. Gioscia-Ryan RA, et al. Among authors: clayton zs. J Physiol. 2021 Feb;599(3):911-925. doi: 10.1113/JP280607. Epub 2020 Oct 28. J Physiol. 2021. PMID: 33103241 Free PMC article.
Late-life voluntary wheel running reverses age-related aortic stiffness in mice: a translational model for studying mechanisms of exercise-mediated arterial de-stiffening.
Gioscia-Ryan RA, Clayton ZS, Fleenor BS, Eng JS, Johnson LC, Rossman MJ, Zigler MC, Evans TD, Seals DR. Gioscia-Ryan RA, et al. Among authors: clayton zs. Geroscience. 2021 Feb;43(1):423-432. doi: 10.1007/s11357-020-00212-1. Epub 2020 Jun 11. Geroscience. 2021. PMID: 32529594 Free PMC article.
Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans.
Brunt VE, Casso AG, Gioscia-Ryan RA, Sapinsley ZJ, Ziemba BP, Clayton ZS, Bazzoni AE, VanDongen NS, Richey JJ, Hutton DA, Zigler MC, Neilson AP, Davy KP, Seals DR. Brunt VE, et al. Among authors: clayton zs. Hypertension. 2021 Aug;78(2):499-511. doi: 10.1161/HYPERTENSIONAHA.120.16895. Epub 2021 May 10. Hypertension. 2021. PMID: 33966451 Free PMC article.
61 results